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Pathol Res Pract ; 248: 154686, 2023 Aug.
Article in English | MEDLINE | ID: mdl-37487315

ABSTRACT

Galbanic acid (GBA), as a natural compound has potential anticancer properties. It has been documented that GBA shows promising therapeutic potential against various types of cancer, including breast, lung, colon, liver, and prostate cancer. Several mechanisms involve im anti-tumor effects of GBA include apoptosis induction, cell cycle arrest, inhibition of angiogenesis, suppression of metastasis, and modulation of immune responses. Furthermore, the synergistic effects of GBA along with chemotherapeutic agents led to has enhancing efficiency with reduction in toxicity. Moreover, GBA through antioxidant and anti-inflammatory properties possess indirect anti-tumor effects. In this review, we will summarize the anti-tumor effects of GBA acid along with involve mechanisms.


Subject(s)
Antineoplastic Agents , Prostatic Neoplasms , Male , Humans , Cell Line, Tumor , Coumarins/pharmacology , Coumarins/therapeutic use , Apoptosis , Antineoplastic Agents/pharmacology , Antineoplastic Agents/therapeutic use
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