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Bone Marrow Transplant ; 46(11): 1430-6, 2011 Nov.
Article in English | MEDLINE | ID: mdl-21243021

ABSTRACT

We retrospectively reviewed medical records of 39 hematopoietic SCT (HSCT) recipients who presented at our hospital between 1 October 2009 and 31 January 2010 with the 2009 H1N1 influenza infection. The median age at presentation was 13.8 years (range: 3.3-56.9), infections developed at a median of 585 days (range: 0-2316) post transplant, the majority (n=27, 69%) occurred in allogeneic HSCT recipients, 12 (31%) patients were on immunosuppressive therapy and 12 (31%) had GVHD. Lower airway disease was present in 8 patients (21%). In total, 15 patients (39%) were hospitalized with a median duration of 4.5 days (range: 3-27 days) and 3 (8%) required mechanical ventilation; 2 of whom died.


Subject(s)
Hematopoietic Stem Cell Transplantation/adverse effects , Influenza A Virus, H1N1 Subtype , Influenza, Human , Adolescent , Adult , Child, Preschool , Female , Graft vs Host Disease/complications , Humans , Immunocompromised Host , Immunosuppression Therapy/adverse effects , Influenza, Human/drug therapy , Influenza, Human/mortality , Male , Middle Aged , Oseltamivir/therapeutic use , Retrospective Studies , Transplantation, Homologous/adverse effects
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