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Rom J Intern Med ; 30(4): 281-4, 1992.
Article in English | MEDLINE | ID: mdl-1299419

ABSTRACT

During 5 years (1986-1990), 81 of the patients under our care showed bronchopulmonary cancer diagnosed by clinical, x-ray and bronchoscopic examinations. Of these, 69 (85.2) were men and 12 (14.8%) women, with a mean age of 62 years; 72 patients (90%) were moderate or heavy smokers. Four of them (4.9%) presented the classical hypertrophic osteoarthropathy (HOA) described by Bamberger and Pierre Marie, i.e., finger clubbing, ossifying periostitis of the long bones, joint pains and swelling. Other 3 patients showed only finger clubbing, while 7 of 30 cases studied by systematic x-ray examinations of the long bones presented ossifying periostitis (5 cases) or hyperostosis (2 cases). It results that almost one third (31.6%) of the patients with bronchopulmonary cancer had a complete or incomplete Bamberger-Pierre Marie syndrome. It is concluded that HOA identification before the clinical and x-ray manifestations of bronchopulmonary cancer could contribute to an early diagnosis of this malignant disease.


Subject(s)
Carcinoma, Bronchogenic/complications , Carcinoma, Squamous Cell/complications , Lung Neoplasms/complications , Osteoarthropathy, Secondary Hypertrophic/etiology , Carcinoma, Bronchogenic/diagnosis , Carcinoma, Bronchogenic/epidemiology , Carcinoma, Squamous Cell/diagnosis , Carcinoma, Squamous Cell/epidemiology , Female , Humans , Incidence , Lung Neoplasms/diagnosis , Lung Neoplasms/epidemiology , Male , Middle Aged , Osteoarthropathy, Secondary Hypertrophic/diagnosis , Osteoarthropathy, Secondary Hypertrophic/epidemiology , Romania/epidemiology
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