Evaluation of the Effect of Nanographene Oxide on Microleakage of Conventional and Resin-Modified Glass Ionomer.

Objectives: One of the important features of the restorative materials is the ability to seal and prevent the microleakage. Glass ionomer cement (GIC) still exhibits some microleakage despite establishing a chemical bond to the tooth. The aim of this study was to evaluate the effect of nanographene oxide (nGO) on the microleakage of conventional (CGIC) and resin-modified glass ionomer cement (RMGIC). Methods: Thirty intact extracted molars were used. Class V cavities were prepared on their buccal and lingual surfaces. The samples randomly divided into two main groups of CGIC and RMGIC; each of them was randomly subdivided into three subgroups, including the group without nGO (control), the group with 1% nGO, and the group with 2% nGO. After restoring the cavities, they were subjected to thermocycling (1,000 cycles at 5/55°C). Two percent basic fuchsin solution was used to perform the microleakage test, and then the sectioned samples were examined by a stereomicroscope 40x. Kruskal-Wallis test, Dunn's test, and Mann-Whitney U test were used to analyze the data (P < 0.05). Results: Group CGIC + 1% nGO at the gingival margin and group RMGIC + 1% nGO at both gingival and occlusal margins had significantly less microleakage than their control groups (P=0.008, P=0.002, P=0.023, respectively). Also, in these two groups, there were no significant differences between the microleakage of the occlusal and gingival margins (P=0.132, P=0.511, respectively), while in all other groups, the gingival microleakage was significantly higher than that of occlusal microleakage. Conclusions: The addition of 1% nGO significantly reduced the gingival microleakage of CGIC and the occlusal and the gingival microleakage of RMGIC, while the addition of 2% nGO did not cause a significant reduction in microleakage.

Evaluation of the effect of nano-graphene oxide on shear bond strength of conventional and resin-modified glass ionomer cement.

OBJECTIVES: Recently, nano-graphene oxide (nGO), a material with unique mechanical properties, has been introduced to improve the properties of glass ionomer cement (GIC). The purpose of this study was to investigate the effect of adding nGO on the shear bond strength (SBS) of conventional (CGIC) and resin-modified GIC (RMGIC). METHODS: Sixty intact molars were mounted and their occlusal surface was cut at a depth of 1 mm below the dentinoenamel junction. 1 wt.% and 2 wt.% of nGO (US Research Nanomaterials, Inc.) were added to CGIC and RMGIC (GC Corporation). The samples were randomly divided into six groups (n = 10), including 1: CGIC,  2: CGIC + 1% GO, 3: CGIC + 2% GO, 4: RMGIC, 5: RMGIC + 1% GO, and 6: RMGIC + 2% GO. Plastic molds were placed on the surface of the dentin pretreated with 10% polyacrylic acid (GC Corporation) and filled with prepared cement according to the manufacturer's instruction. After 24 h of storage in an incubator, the SBS test was done by the universal testing machine. Data were analyzed using two-way analysis of variance and post hoc Tukey tests (p < .05). RESULTS: In the group of CGIC, mean SBS was significantly lower than all other study groups (p < .001), and groups 5 (RMGIC + 1% GO) and 6 (RMGIC + 2% GO) showed significantly higher values compared to all other study groups (p < .001). However, the difference between groups 2 and 3, as well as the difference between groups 5 and 6, was not significant (p = .999 andp = .994, respectively). RMGI groups had significantly higher SBS than their corresponding CGIC groups. CONCLUSIONS: The addition of 1% and 2% nGO significantly increased the SBS of CGIC and RMGIC to the dentin, which can be considered as a promising point for wider clinical application of this material.

Sudden Death Following Exercise; a Case Series.

INTRODUCTION: Natural and unexpected death that happens within less than one hour of first symptom occurrence is called sudden death. Cardiovascular diseases are the main known reason of sudden death and more than 75% of sudden deaths in athletes are assigned to it. Here we reported the autopsy results of all cases with sudden death following exercise that were referred to forensic center of Tehran, Iran, from 2009 to 2014. METHODS: In this cross sectional study all subjects who were registered to forensic medicine center of Tehran, Iran, from 2009 to 2014, as a case of sudden death following exercise were evaluated. Demographic data and medical history as well as autopsy and toxicology findings were retrospectively gathered using profiles of the deceased. Results were reported using descriptive analysis. RESULTS: 14 cases were registered as sudden death following exercise in forensic medicine profiles during the study period. Exploring the files of the mentioned deceased, revealed five non-compatible cases in this regard. Finally, 9 eligible cases were enrolled (88.9% male). The mean age of the deceased was 28.66 ± 10.86 years (range: 7 - 40). Toxicological tests were available for 7 cases, one of which was positive for tramadol. Sudden death following football was reported most frequently (44.4%). Only 3 (33.3%) cases had herald signs such as chest pain, syncope, or loss of consciousness. 1 case (11.11%) had a positive history of sudden death in relatives. CONCLUSION: Although most sudden death victims are asymptomatic until the event, all those who suffer from symptoms such as chest pain, shortness of breath, dizziness, fatigue and irregular heart rate during physical activities, should be screened regarding common probable causes of sudden death.

Effects of maxillary expansion and placebo effect of appliances on nocturnal enuresis - preliminary results.

INTRODUCTION: Nocturnal enuresis has been found a common symptom among children with breathing problems and sleep apnea. The purpose of this study was to evaluate the therapeutic and placebo effects of slow maxillary expansion on nocturnal enuresis. MATERIAL AND METHODS: Four children with enuresis aged 7-12 years were selected. Rigid acrylic expansion appliances were fabricated and delivered to them. Frequency of enuresis was recorded by the parents during three stages: 1) before appliance delivery; 2) after appliance insertion without expansion; and 3) during expansion and retention. RESULTS: The frequency of wetting decreased significantly during the period of appliance use without expansion. During the expansion and retention phase, two patients became completely dry, and two patients improved significantly. CONCLUSIONS: Maxillary expansion can have a positive effect on the treatment of nocturnal enuresis. Also, the placebo effect of the expansion appliance has significant effects on enuresis.