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1.
Sci Rep ; 6: 37239, 2016 11 24.
Article in English | MEDLINE | ID: mdl-27883031

ABSTRACT

Colloidal clay in water suspensions are known to exhibit a multitude of bulk phases depending on initial colloidal concentration and ionic strength, and examples of this include repulsive Wigner colloidal glasses at low ionic strength and attractive gels at higher ionic strength due to screened electrostatic forces by the electrolyte. From confocal Raman microscopy combined with elasticity measurements, we infer that clay trapped at quasi two-dimensional interfaces between oil and water also exhibit confined glass-like or gel-like states. The results can be important for the preparation of particles stabilized colloidal emulsions or colloidal capsules, and a better understanding of this phenomenon may lead to new emulsion or encapsulation technologies.

2.
Expert Opin Drug Deliv ; 5(12): 1335-55, 2008 Dec.
Article in English | MEDLINE | ID: mdl-19040396

ABSTRACT

Many researchers all over the world are exploring various methods to find better insulin delivery routes for diabetic patients. Microencapsulation in biodegradable polymeric matrices is the source of developing new insulin formulations. This paper will attempt to explain the techniques utilized for insulin microencapsulation, their specifications and the parameters that influence the process. This review takes a closer look at recent researches and methods that have been reported in this decade.


Subject(s)
Drug Compounding/methods , Drug Delivery Systems , Hypoglycemic Agents/administration & dosage , Insulin/administration & dosage , Biocompatible Materials/chemistry , Biocompatible Materials/pharmacology , Emulsions , Humans , Hypoglycemic Agents/chemistry , Insulin/chemistry , Nanoparticles/chemistry , Polymers/chemistry , Polymers/pharmacology
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