ABSTRACT
One of the main goals in the rehabilitation process of patients with burn to their hands is their return to society and their professional occupation, which has a direct positive influence on these patients' quality of life. The goal of this research project was to investigate the effect of early intervention with occupational therapy in patients with burns to their hands. The study included 30 patients with second or third degree hand burns. Patients were added to the study 12 days after their burn wounds and grafted areas had healed. They had 3 sessions of occupational therapy per week for 8 weeks. These sessions included active and passive range of motion exercises, active resistive exercises, stretching exercises and practicing activities of daily living. Functionality of the hand was assessed before and after the 8 weeks of occupational therapy using the DASH questionnaire. The average initial DASH score before intervention with occupational therapy was 60.9, and after 8 weeks of occupational therapy it was 33.9 (average difference between the pre-intervention and post-intervention DASH scores is 27 points, p < 0.001). After 8 weeks of occupational therapy, patients performed activities of daily living with a lot less difficulty, and an increase in functionality of the hands was observed. This study suggests that early intervention with rehabilitative therapies is advantageous and may result in improved hand function.
Un des buts de la rééducation des patients aux mains brûlées est la réinsertion à la société et au travail, ce qui a une influence directe sur leur qualité de vie. Le but de cette étude était d'évaluer l'effet de l'introduction précoce de l'ergothérapie dans le programme de rééducation de 30 patients brûlés des mains (2ème et 3ème degrés). Ce programme, comprenant 3 séances d'ergothérapie hebdomadaires pendant 8 semaines, débutait 12 j après la cicatrisation. Les séances comportaient des exercices moteurs actifs et passifs, des exercices actifs contre résistance, des étirements et des exercices mimant les mouvements de la vie quotidienne. Les capacités fonctionnelles des mains étaient évaluées avant et en fin de programme, en utilisant le questionnaire DASH. Il était initialement de 60,9 et de 33,9 en fin de programme (différence 27 points, p< 0,001). Après 8 semaines d'ergothérapie, les patients avaient beaucoup moins de difficulté à réaliser les gestes de la vie courante et on observait une augmentation des capacités fonctionnelles des mains. Cette étude suggère que l'introduction précoce de l'ergothérapie peut permettre une amélioration de la fonction des mains brûlées.
ABSTRACT
BACKGROUND: Knowledge of factors associated with quality of life in patients with thalassemia is necessary for creating appropriate clinical programs, social support, and improving treatment outcomes. The purpose of this study was to determine quality of life in children with thalassemia major at Center for Special Diseases of valiasr hospital in Birjand. MATERIALS AND METHODS: This cross-sectional descriptive-analytical study was conducted on 40 children over 7 years of age with thalassemia major. Tools for data collection included a demographic questionnaire and World Health Organization Quality of Life questionnaire (WHOQOL- Bref) standard questionnaire comprising 26 items to determine quality of life in patients with thalassemia. Data was analyzed using descriptive statistical tests (mean, SD, and frequency), and inferential statistical test (t-test) in SPSS software. RESULTS: Results showed mean score of 70.37±9.88 for quality of life, 25±3.06 for physical health, 18.12±3.22 for mental health, 21.3±4.43 for living environment, and 5.95±1.58 for sociability. There was no significant correlation between quality of life and demographic variables. Correlation between social relationships and education level was significant (P-value<0.0001). CONCLUSION: According to the results, quality of life of the patient was above average in three dimensions of physical health, psychological health, and environmental health, and in order to improve quality of life in these children, appropriate programs should be implemented to support them physically, mentally and socially, and improve patient's relationship with Center for Special Diseases.
ABSTRACT
The development of reliable processes for the synthesis of silver nanomaterials is an important aspect of current nanotechnology research. In this work, silver nanoparticles were produced in a bioreactor by Escherichia coli (E. coli). For this purpose, a process was designed and silver nanoparticles at a scale larger than laboratorial scale were produced by considering optimum conditions and using E. coli. This research for the first time was carried out at a scale larger than laboratory scale indicating ability to produce nanoparticles at a large scale using microorganisms. In addition, UV-vis spectroscopy, atomic absorption spectroscopy (AAS), transitional electron microscopy (TEM) and dynamic light scattering (DLS) were employed to investigate characterisation of nanoparticles.
