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1.
Autops Case Rep ; 11: e2020226, 2021.
Article in English | MEDLINE | ID: mdl-34277490

ABSTRACT

Uterine rupture during pregnancy is a known complication of placenta accreta. This paper presents a case of sudden maternal death in the 27th week of gestation due to a ruptured uterine scar at the site of placenta accreta with a short inter-pregnancy period of 6 months with previous two C-sections. Autopsy findings revealed a massive hemoperitoneum and a thinned out anterolateral uterine wall. Internal examination revealed clotted and fluid blood in the peritoneal cavity with rupture of the anterior uterine wall at the site of the placenta accreta in a healed cesarean section scar. Placenta accreta is a rare complication of pregnancy. However, it is becoming more frequent and a significant risk factor with the increasing rate of C-section.

2.
Autops. Case Rep ; 11: e2020226, 2021. graf
Article in English | LILACS | ID: biblio-1142402

ABSTRACT

Uterine rupture during pregnancy is a known complication of placenta accreta. This paper presents a case of sudden maternal death in the 27th week of gestation due to a ruptured uterine scar at the site of placenta accreta with a short inter-pregnancy period of 6 months with previous two C-sections. Autopsy findings revealed a massive hemoperitoneum and a thinned out anterolateral uterine wall. Internal examination revealed clotted and fluid blood in the peritoneal cavity with rupture of the anterior uterine wall at the site of the placenta accreta in a healed cesarean section scar. Placenta accreta is a rare complication of pregnancy. However, it is becoming more frequent and a significant risk factor with the increasing rate of C-section.


Subject(s)
Humans , Female , Pregnancy , Adult , Placenta Accreta , Uterine Rupture , Cesarean Section , Maternal Death , Pregnancy Complications , Autopsy , Cicatrix , Fatal Outcome , Death, Sudden
3.
Autops Case Rep ; 10(4): e2020223, 2020 Nov 20.
Article in English | MEDLINE | ID: mdl-33344331

ABSTRACT

The Left anterior descending artery (LAD) is a branch of the left main coronary artery which runs obliquely towards the apex of the heart in the anterior interventricular sulcus. Among all of the coronary arteries, the LAD artery has the most constant course. Amongst the anomalies of coronaries, the duplication or bifurcation of the LAD artery is infrequent. The classification of the bifurcation of the LAD has been extensively described in various reports with the widespread use of CT Angiography. We describe herein, an anomalous LAD detected on autopsy. This unusual case highlights the gross autopsy finding of Type-I anomalous dual LAD coronary artery in a young adult who died of Myocardial Infarction.

4.
Autops. Case Rep ; 10(1): e2020146, Jan.-Mar. 2020. tab, ilus
Article in English | LILACS | ID: biblio-1053539

ABSTRACT

Phosphorus is a nonmetallic irritant used in various sectors like rodenticide, firecracker industries, match industries, and fertilizers. Phosphorus poisoning is responsible for deaths among children and adults. Accidental yellow phosphorus poisoning is frequently reported in children, whereas suicidal consumption is not uncommon amongst adults. Herein, we present the case of a 30-year-old female patient who ingested Ratol paste containing yellow phosphorus in an attempt to commit suicide. Her initial chief complaints were nausea, vomiting along with loose motion during hospitalization, followed by a symptomless phase with stable vitals on the 2nd day, and managed conservatively. She took discharge against the medical advice. Later on, she was readmitted in the same hospital, after two days, complaining of generalized weakness, bodily pain, drowsiness, loss of appetite, and breathing difficulties. She developed severe complications due to the intoxication and died. An autopsy was performed. The histopathological and the toxicological examination were carried out. We found characteristic features in different organs due to yellow phosphorus toxicity. We concluded the cause of death as hepatic encephalopathy and multi-organ dysfunction syndrome caused by the yellow phosphorus poisoning.


Subject(s)
Humans , Female , Adult , Phosphorus/poisoning , Autopsy , Hepatic Encephalopathy/pathology , Fatal Outcome , Multiple Organ Failure/pathology
5.
Autops Case Rep ; 10(1): e2020146, 2020.
Article in English | MEDLINE | ID: mdl-32039071

ABSTRACT

Phosphorus is a nonmetallic irritant used in various sectors like rodenticide, firecracker industries, match industries, and fertilizers. Phosphorus poisoning is responsible for deaths among children and adults. Accidental yellow phosphorus poisoning is frequently reported in children, whereas suicidal consumption is not uncommon amongst adults. Herein, we present the case of a 30-year-old female patient who ingested Ratol paste containing yellow phosphorus in an attempt to commit suicide. Her initial chief complaints were nausea, vomiting along with loose motion during hospitalization, followed by a symptomless phase with stable vitals on the 2nd day, and managed conservatively. She took discharge against the medical advice. Later on, she was readmitted in the same hospital, after two days, complaining of generalized weakness, bodily pain, drowsiness, loss of appetite, and breathing difficulties. She developed severe complications due to the intoxication and died. An autopsy was performed. The histopathological and the toxicological examination were carried out. We found characteristic features in different organs due to yellow phosphorus toxicity. We concluded the cause of death as hepatic encephalopathy and multi-organ dysfunction syndrome caused by the yellow phosphorus poisoning.

6.
Autops. Case Rep ; 10(4): e2020223, 2020. tab, graf
Article in English | LILACS | ID: biblio-1131863

ABSTRACT

The Left anterior descending artery (LAD) is a branch of the left main coronary artery which runs obliquely towards the apex of the heart in the anterior interventricular sulcus. Among all of the coronary arteries, the LAD artery has the most constant course. Amongst the anomalies of coronaries, the duplication or bifurcation of the LAD artery is infrequent. The classification of the bifurcation of the LAD has been extensively described in various reports with the widespread use of CT Angiography. We describe herein, an anomalous LAD detected on autopsy. This unusual case highlights the gross autopsy finding of Type-I anomalous dual LAD coronary artery in a young adult who died of Myocardial Infarction.


Subject(s)
Humans , Male , Adult , Anomalous Left Coronary Artery/pathology , Myocardial Infarction , Autopsy
7.
J Forensic Leg Med ; 28: 42-6, 2014 Nov.
Article in English | MEDLINE | ID: mdl-25440147

ABSTRACT

The aim of the present study is to evaluate the diagnostic efficacy of biochemical markers creatine kinase-MB (CK-MB) and LDH in pericardial fluid for postmortem diagnosis of ischemic heart disease (IHD). We studied 119 medico-legal autopsies selected during a period of 2 years. Subjects were assigned into diagnostic groups upon final cause of death as follows: (1) sudden cardiac death due to IHD's (n = 52), (2) violent asphyxia (n = 24); (3) polytraumatic deaths (n = 20); (4) natural deaths excluding cardiac causes (n = 23). Pericardial fluid samples were tested for estimating enzyme levels. Histological examination was performed with hematoxylin and eosin (H&E) stain on myocardial tissue samples. We observed highest levels of CK-MB & LDH in deaths due to IHD's. Kruskal-Wallis test revels significant differences in activities of CK-MB (P = 0.0001) and LDH (P = 0.0065) amongst all diagnostic groups. Mann-Whitney test showed highly significant (P < 0.0001) levels of CK-MB in group 1 as compared to other diagnostic groups. However, LDH levels were non-discriminatory (P = 0.0827) between cases of IHD's and cases of other natural deaths. CK-MB levels were statistically non-significant between cases divided as myocardial infarction (MI) and severe coronary artery disease in group 1, hence its role for postmortem detection of MI is somewhat limiting. However, sensitivity and negative predictive values of its cut off level obtained in cases of IHD's are nearly equal to diagnostic efficacy in clinical settings. Hence, it can be useful additional diagnostic tool for autopsy diagnosis of IHD's. Whereas, LDH is not useful for postmortem diagnosis in these cases.


Subject(s)
Creatine Kinase, MB Form/analysis , L-Lactate Dehydrogenase/analysis , Myocardial Ischemia/metabolism , Pericardium/chemistry , Autopsy , Biomarkers , Coronary Artery Disease/metabolism , Diagnosis, Differential , Humans , Myocardial Infarction/metabolism
8.
J Forensic Leg Med ; 26: 19-23, 2014 Aug.
Article in English | MEDLINE | ID: mdl-25066168

ABSTRACT

Violence runs into the fabric of society. In recent years, violence has been identified as an important health problem in industrialised societies. In the present study, conducted to analyze injury characteristics, 813 victims of interpersonal violence presenting to emergency department at a Government Medical College and Hospital from a major city in Central India were interviewed and examined over a period of one year. Central to the quantitative analysis of the data collected was the extraction of specific injury characteristics from the sample population. The group included 606 men and 207 females, most of them were resident of urban areas, aged between 11 and 30 years. Most of attacks occurred at nights, with minimal seasonal variation. Males were more commonly attacked outdoors by a single stranger male while females were mostly attacked indoors by spouse. Blunt trauma was more commonly seen in females as compared to males. Head neck and face region was the most preferred anatomical site by the assailants. Hard and blunt weapons were used more commonly at homes (184 of 269 incidents) than at streets (301 of 561 incidents). Sharp edged and pointed weapons were most commonly used at streets. Firearms were rarely used. Occurrence of physical assaults in this region more or less follows the pattern seen in other parts of the world with local and socio-cultural differences that need to be further delved into and considered during the planning and implementation of injury prevention programs.


Subject(s)
Crime Victims/statistics & numerical data , Emergency Service, Hospital , Violence/statistics & numerical data , Wounds and Injuries/epidemiology , Adolescent , Adult , Age Distribution , Alcohol Drinking/epidemiology , Child , Criminals/statistics & numerical data , Female , Humans , India/epidemiology , Male , Sex Distribution , Urban Population , Weapons/statistics & numerical data , Wounds and Injuries/etiology , Young Adult
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