A rare presentation of dengue fever: bilateral psoas muscle hematoma, intrahepatic cholestatic hepatitis, pancreatitis and pancytopenia.

Dengue is the foremost cause of arthropod-borne viral disease in the world. It is and commonly found in tropical and subtropical parts of the world. Dengue fever is caused by one of the four distinct serotypes (DENV 1-4) of single-stranded RNA Flavivirus genus and transmitted through Aedes mosquito. Infection caused by one serotype develops lifelong immunity to that serotype, but not to others. Dengue fever (DF) presents with high fever, headache, myalgia, and arthralgia, and rash. Severe dengue, dengue haemorrhagic fever (DHF), and dengue shock syndrome (DSS) are accompanied by thrombocytopenia, vascular leakage, and hypotension. DSS is characterized by shock, which can be fatal with case fatality high as 12% to 44%. There are few atypical manifestations of dengue fever growing with rising disease burden, often missed and sometimes difficult to diagnosis. In this case report, we will discuss atypical manifestations of bilateral psoas muscle hematoma, intrahepatic cholestatic hepatitis, pancreatitis and pancytopenia observed in dengue fever patient.

Clinical Utility of Arterial Spin Labeling Magnetic Resonance Imaging in the Evaluation of the Brain.

Introduction: Cerebral blood flow (CBF) is essential for studying the brain in both normal and diseased states. Arterial spin labeling (ASL) is a functional magnetic resonance imaging (MRI) technique that uses arterial water as an endogenous tracer to measure CBF, thus does not require an injection of exogenous tracers and is noninvasive and can therefore be used to track changes in CBF. Materials and Methods: This prospective, observational and descriptive study was done at the department of imaging, Maxcure Hospital, Hyderabad, for the duration of 18 months. All studies were performed on a 1.5T Philips Prodiva CX using a phased array coil. Results: A prospective observational and descriptive study was done among 100 patients to study the clinical utility of ASL. Out of 100 patients, 20 (20%) patients showed normal MRI findings. Rest 80 (80%) patients had abnormal MRI findings. Conclusion: ASL provides additional and complementary information to that available from structural MRI in all categories of abnormalities.