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Sci Rep ; 13(1): 4895, 2023 03 25.
Article in English | MEDLINE | ID: mdl-36966257

ABSTRACT

Ectopic fat deposition is more strongly associated with obesity-related health problems including type 2 diabetes mellitus (T2DM), cardiovascular diseases (CVD), hypothyroidism, arthritis, etc. Our study aimed at identifying the cumulative role of several risk factors in developing obesity and the role of ectopic fat (visceral fat) in predicting cardiovascular disease risk in varied age groups among urban adult academic professionals in West Bengal. 650 adults (Male = 456; Female = 194) associated with the academic job (age 20-65 years) in urban West Bengal were randomly selected for anthropometric, blood biochemical, and questionnaire-based analyses. Body Mass Index and Visceral Fat% exhibited comparable association with all the other anthropometric parameters (e.g. Whole body Subcutaneous fat%: male-Linear Regression Comparison: F = 11.68; P < 0.001; female-F = 6.11; P < 0.01). Therefore, VF% acts as a risk factor alongside BMI in instances where BMI fails alone. The presence of T2DM, hypertension, and hypothyroidism in the case groups confirmed their obesity-associated longitudinal pattern of inheritance. Unhealthy diet pattern indicates improper liver function, vitamin D deficiency, and increased erythrocytic inflammation. An overall sedentary lifestyle with parental history of obesity was found to be significant in the longitudinal transmission of the disease.


Subject(s)
Cardiovascular Diseases , Diabetes Mellitus, Type 2 , Humans , Adult , Male , Female , Young Adult , Middle Aged , Aged , Diabetes Mellitus, Type 2/complications , Sedentary Behavior , Obesity/complications , Obesity/epidemiology , Risk Factors , Cardiovascular Diseases/etiology , Epidemiologic Studies , Body Mass Index , India/epidemiology
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