A study of the adjuvant effect of nigrosin on antibody synthesis and phagocytic activity of peritoneal macrophages of inbred mice.

The dye nigrosin has an adjuvant effect on the synthesis of specific IgE and hemagglutinating antibodies in B6D2F1 mice. Phagocytosis of opsonized sheep red blood cells by peritoneal macrophages was enhanced by treatment with the dye, indicating a possible increase in the expression of Fc and C3b receptors of macrophages.