ABSTRACT
This study examined the naturally occurring dimensions of the dentogingival junction in 10 adult human cadaver jaws. The connective tissue attachment, epithelial attachment, loss of attachment, and sulcus depth were measured histomorphometrically for 171 tooth surfaces. Mean measurements were 1.34 +/- 0.84 mm for sulcus depth; 1.14 +/- 0.49 mm for epithelial attachment; 0.77 +/- 0.32 mm for connective tissue attachment; and 2.92 +/- 1.69 mm for loss of attachment. These dimensions, as measured in this study, support the concept that the connective tissue attachment is a variable width within a more narrow distribution and range than the epithelial attachment, sulcus depth, or loss of attachment. The level of the loss of attachment was not predictive of the connective tissue attachment length.
Subject(s)
Periodontal Attachment Loss/pathology , Periodontium/anatomy & histology , Aged , Connective Tissue/anatomy & histology , Epithelial Attachment/anatomy & histology , Gingiva/anatomy & histology , Humans , Middle Aged , Reference Values , Regression AnalysisABSTRACT
Three types of paper-covered and one type of plastic-covered Kodak dental film were used to determine if bacteria could penetrate the coverings and contaminate the inner film. Films from each group were immersed for 30 or 120 seconds in high concentrations of known bacterial suspensions with or without 10% sterilized calf serum added to the incubation media. The plastic-covered film effectively excluded all bacteria, whereas the paper-covered film showed contamination with all organisms even at 30 seconds. Increasing the viscosity of the incubation medium with calf serum decreased the level of contamination.
Subject(s)
Equipment Contamination/prevention & control , Radiography, Dental/instrumentation , X-Ray Film , Bacillus subtilis , Colony Count, Microbial , Cross Infection/prevention & control , Mouth/microbiology , Mycobacterium , Paper , Plastics , Pseudomonas aeruginosa , Staphylococcus aureusABSTRACT
Two phosphorothioate compounds, WR-2721 and WR-151327, were examined for their radioprotective efficacies against the effects of fission neutron irradiation in male and female mice. Within sex groups no significant difference in lethality at 30 or 100 days postirradiation was found between WR-2721 or WR-151327 pretreatment. The dose modification factors (DMFs) for male mice treated with either compound were 1.29 (LD50/30) and 1.24 (LD50/100), and those for drug-treated female mice were 1.21 (LD50/30) and 1.19 (LD50/100). Both WR-2721 and WR-151327 were found to be equally radioprotective when compared using DMFs as the end point. WR-151327 (500 mg/kg, ip) was found to be significantly more toxic to both male and female B6D2F1 mice than equimolar amounts of WR-2721. Small but significant sex differences in radioprotection were found: the DMFs for female mice pretreated with either compound were lower than those for similarly treated male mice; the incidence of mortality 31-100 days postexposure in male mice pretreated with WR-151327 was greater than for female mice. In addition, sex differences were noted in drug toxicity. Toxic death in female mice given WR-151327 (500 mg/kg, ip) is 2.6 times more probable than in males.
