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7.
Br J Vener Dis ; 57(1): 20-4, 1981 Feb.
Article in English | MEDLINE | ID: mdl-7470831

ABSTRACT

The concentrations of immunoglobulins G, A, and M were measured in 62 samples of cerebrospinal fluid from 35 patients with asymptomatic neurosyphilis, 18 with symptomatic neurosyphilis, and nine with late syphilis of other organs. The most frequent and highest increase in IgG and IgA occurred in patients with symptomatic neurosyphilis. IgM was found in only five patients, but its presence, together with an increase in IgG and IgA concentrations, appears to indicate activity of the pathological process and a poor prognosis for the course of the disease.


Subject(s)
Immunoglobulin A/cerebrospinal fluid , Immunoglobulin G/cerebrospinal fluid , Immunoglobulin M/cerebrospinal fluid , Syphilis/cerebrospinal fluid , Adult , Aged , Cerebrospinal Fluid Proteins/analysis , Female , Humans , Leukocyte Count , Lymphocytes , Male , Middle Aged , Neurosyphilis/cerebrospinal fluid , Neurosyphilis/pathology , Syphilis/pathology
13.
Br J Vener Dis ; 56(1): 17-9, 1980 Feb.
Article in English | MEDLINE | ID: mdl-6989444

ABSTRACT

Sera from 3028 patients attending a dermatological clinic were examined by the fluorescent treponemal antibody (FTA) test, the fluorescent antibody-absorbed (FTA-ABS) test, the Venereal Disease Research Laboratory (VDRL) test, and Kolmer's test. Eleven cases of late syphilis were found. Sera from 63 (2.08%) of the remaining 3017 patients showed non-specific results; these were found more frequently in patients with pyodermas, neoplasms, acne, mycoses, crural ulceration, and psoriasis than in those with other diseases. No non-specific results were observed in patients with bullous skin diseases and only a few in patients with viral skin diseases and chronic lupus erythematosus. The test producing the most non-specific results was the FTA test, followed by the FTA-ABS test, the VDRL test, and Kolmer's test.


Subject(s)
Skin Diseases/immunology , Syphilis Serodiagnosis/methods , Antibodies, Bacterial/analysis , False Positive Reactions , Fluorescent Antibody Technique , Humans , Treponema Immobilization Test , Treponema pallidum/immunology
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