1.
Org Lett
; 2(21): 3269-71, 2000 Oct 19.
Article
in English
| MEDLINE
| ID: mdl-11029187
ABSTRACT
Baccatin III forms crystalline complexes 4 and 5 with imidazole and 2-propanol, respectively. These compounds are useful in the purification of baccatin III from mixtures of taxanes derived from plant-cell fermentation.
Subject(s)
2-Propanol/chemistry , Alkaloids/chemical synthesis , Imidazoles/chemistry , Taxoids , Alkaloids/chemistry , Alkaloids/isolation & purification , Crystallography, X-Ray , Drugs, Chinese Herbal , Models, Molecular , Molecular Structure , Protein Conformation
2.
Org Lett
; 2(21): 3281-3, 2000 Oct 19.
Article
in English
| MEDLINE
| ID: mdl-11029190
ABSTRACT
The anticancer drug etoposide, 1, is prepared in 79% overall yield from readily available 4'-demethyl-4-epipodophyllotoxin, 3, and 4, 6-O-ethylidene-2,3-O-dibenzyl-D-glucose, 4, via a crystallization-induced stereoselective glycosidation reaction followed by catalytic hydrogenation.
Subject(s)
Antineoplastic Agents, Phytogenic/chemical synthesis , Etoposide/chemical synthesis , Glycosides/chemistry , Antineoplastic Agents, Phytogenic/chemistry , Crystallization , Etoposide/chemistry , Stereoisomerism
3.
J Nutr
; 100(5): 491-7, 1970 May.
Article
in English
| MEDLINE
| ID: mdl-5429520
Subject(s)
Brain/metabolism , Nerve Tissue Proteins/metabolism , RNA/biosynthesis , Zinc/metabolism , Animal Nutritional Physiological Phenomena , Animals , Body Weight , Brain/anatomy & histology , Brain/physiology , Carbon Isotopes , Cerebellum/metabolism , Deficiency Diseases/metabolism , Diet , Injections , Injections, Intraperitoneal , Kidney/anatomy & histology , Kidney/metabolism , Leucine/metabolism , Liver/anatomy & histology , Liver/metabolism , Male , Medulla Oblongata/metabolism , Nerve Tissue Proteins/biosynthesis , Organ Size , Organ Specificity , Ovalbumin , Pons/metabolism , Rats , Time Factors , Tritium , Uridine/metabolism , Zinc/administration & dosage , Zinc Isotopes
4.
Proc Soc Exp Biol Med
; 127(3): 712-6, 1968 Mar.
Article
in English
| MEDLINE
| ID: mdl-5689926
