ABSTRACT
Adipose tissue blood flow is measured from the clearance of radioactive xenon from a depot. Traditionally, a NaI detector has been used to measure the residual depot of xenon. However, this is sensitive to movement artefacts. We tested a commercially available lightweight CsI detector which can be strapped to the anterior abdominal wall. In pilot studies the CsI detector produced higher values for adipose tissue blood flow than did a conventional NaI detector. It was modified by inclusion of spacers to distance it from the skin. Flow results generated by the modified detector were similar to those generated by the NaI detector, both after an overnight fast and during the increased blood flow after a meal. Individual decay patterns generated by the CsI detector were, however, significantly smoother than those from the NaI detector.
Subject(s)
Adipose Tissue/blood supply , Abdominal Muscles/physiology , Adult , Cesium , Eating/physiology , Fasting/physiology , Female , Humans , Iodides , Male , Middle Aged , Pilot Projects , Regional Blood Flow/physiology , Skin/blood supply , Sodium Iodide , Xenon RadioisotopesSubject(s)
Myocardial Infarction/complications , Acute Disease , Arrhythmias, Cardiac/etiology , Cardiac Output , Heart Aneurysm/etiology , Heart Failure/etiology , Heart Ventricles , Humans , Myocardial Infarction/physiopathology , Myocardial Infarction/therapy , Papillary Muscles/physiopathology , Time FactorsABSTRACT
In 29 patients, the site and extent of coronary artery obstruction were related to the position and area of abnormally contracting segments of the left ventricle, both in patients with a history of angina without myocardial infarction (group I) and in patients with prior documented myocardial infarction (group II). The degree of coronary artery obstructive disease was estimated in the standard manner and also by a coronary artery index which considered not only the degree of obstruction but also the total length of the obstructed segment. A kinetic or dyskinetic segments were present in 22 of the 29 patients. An abnormally contracting segment was present in 12 or 18 patients without prior myocardial infarction in comparison with 10 of the 11 patients with prior infarction. Complete obstruction of a coronary vessel and resultant dyskinesia were more frequent in the right coronary artery than in either the left anterior descending or the circumflex artery. There was a significant correlation between total per cent of vessel obstruction and degree of ventricular asynergy in both groups; consideration of length of obstructed segment did not improve this correlation.
