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1.
Equine Vet J ; 46(1): 92-6, 2014 Jan.
Article in English | MEDLINE | ID: mdl-23662918

ABSTRACT

REASONS FOR PERFORMING STUDY: Computed tomography (CT) is increasingly accessible in equine referral hospitals. OBJECTIVES: To document the level of agreement within and between radiography and CT in characterising equine distal limb fractures. STUDY DESIGN: Retrospective descriptive study. METHODS: Images from horses that underwent radiographic and CT evaluation for suspected distal limb fractures were reviewed, including 27 horses and 3 negative controls. Using Cohen's kappa and weighted kappa analysis, the level of agreement among 4 observers for a predefined set of diagnostic characteristics for radiography and CT separately and for the level of agreement between the 2 imaging modalities were documented. RESULTS AND CONCLUSIONS: Both CT and radiography had very good intramodality agreement in identifying fractures, but intermodality agreement was lower. There was good intermodality and intramodality agreement for anatomical localisation and the identification of fracture displacement. Agreement for articular involvement, fracture comminution and fracture fragment number was towards the lower limit of good agreement. There was poor to fair intermodality agreement regarding fracture orientation, fracture width and coalescing cracks; intramodality agreement was higher for CT than for radiography for these features. POTENTIAL RELEVANCE: Further studies, including comparisons with surgical and/or post mortem findings, are required to determine the sensitivity and specificity of CT and radiography in the diagnosis and characterisation of equine distal limb fractures.


Subject(s)
Extremities/injuries , Fractures, Bone/diagnostic imaging , Horse Diseases/diagnostic imaging , Horses/injuries , Tomography, X-Ray Computed/veterinary , Animals , Extremities/diagnostic imaging , Fractures, Bone/pathology
2.
Vet Comp Oncol ; 12(1): 67-77, 2014 Mar.
Article in English | MEDLINE | ID: mdl-22738696

ABSTRACT

Brain neoplasia is diagnosed in an increasing number of dogs. Consequently, there is a higher need for an effective treatment. Chemotherapy is considered in cases where surgery or radiation is not optional. The objective of this retrospective study was to evaluate the difference in median survival time (MST) of dogs with intracranial masses, treated symptomatically with corticosteroids and anti-epileptic drugs, compared with the same symptomatic treatment supplemented with lomustine. The records of 71 dogs with intracranial masses were retrospectively evaluated. Fifteen dogs were treated symptomatically with corticosteroids and anti-epileptics, and 56 dogs received additional therapy with lomustine. There was no statistically significant difference in MST between both groups, being 60 and 93 days, respectively. Age, duration of symptoms, intracranial localization of the mass and intra- or extra-axial localization had no influence on survival time. However, female dogs survived significantly longer than male dogs.


Subject(s)
Antineoplastic Agents, Alkylating/therapeutic use , Brain Neoplasms/veterinary , Dog Diseases/drug therapy , Lomustine/therapeutic use , Animals , Brain Neoplasms/drug therapy , Dogs , Female , Male , Retrospective Studies
3.
Equine Vet J ; 42(4): 367-71, 2010 May.
Article in English | MEDLINE | ID: mdl-20525057

ABSTRACT

A 5-year-old Rheinlander gelding was evaluated for left hindlimb stifle lameness. The lameness was localised to the stifle, but source of the lameness was not specifically diagnosed from the physical, radiographic and ultrasonographic examinations. Computed tomography (CT) and CT arthrography were therefore used for further investigation since these imaging techniques image bony structures, cartilage and soft tissues. This examination showed multiple lesions in the stifle: an osteochondrosis dissecans like lesion of the medial femoral condyle, bony fragments, cartilage trauma and caudal cruciate ligament injury. The prognosis for continuing use as a sports horse was regarded as unfavourable. Therefore, the horse was subjected to euthanasia. All CT findings were confirmed by gross pathology. The CT and CT arthrography examination in this case provided a diagnosis not achieved with other conventional imaging techniques.


Subject(s)
Fractures, Cartilage/veterinary , Horse Diseases/diagnostic imaging , Horses/injuries , Stifle/diagnostic imaging , Stifle/injuries , Tomography, X-Ray Computed/veterinary , Animals , Arthrography/veterinary , Fractures, Cartilage/diagnostic imaging , Fractures, Cartilage/pathology , Horse Diseases/pathology , Male , Stifle/pathology
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