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1.
Neurol Neurochir Pol ; 13(3): 251-4, 1979.
Article in Polish | MEDLINE | ID: mdl-471157

ABSTRACT

The authors determined the leukergic reaction in the blood of multiple sclerosis patients treated with dexamethasone and sodium salicylate. The investigations were done in two groups of 25 patients each. Dexamethasone was used in a daily dose of 4 mg, and sodium salicylate in a dose of 2.0 g. A significant effect of dexamethasone on reduction of the leukergic forms of leucocyte in the peripheral blood of these patients was observed. There was no significant effect of sodium salicylate on leukergy.


Subject(s)
Dexamethasone/therapeutic use , Leukocytes/physiology , Multiple Sclerosis/blood , Sodium Salicylate/therapeutic use , Adolescent , Adult , Cell Adhesion/drug effects , Dexamethasone/pharmacology , Female , Humans , Leukocytes/drug effects , Male , Middle Aged , Multiple Sclerosis/drug therapy , Sodium Salicylate/pharmacology
2.
Neurol Neurochir Pol ; 12(1): 35-8, 1978.
Article in Polish | MEDLINE | ID: mdl-634430

ABSTRACT

The authors determined peripheral-blood ammonia level in patients with cerebral strokes. The determinations were done by the method of Konitzer et al. on the 1st, 3rd and 7th days of the disease. The results of determinations were subjected to statistical analysis with the t test of Student. It was found that the mean serum ammonia level in patients with cerebral stroke on the 1st day of the disease was higher than in the control group. The difference was statistically significant. The level of ammonia in the blood of patients with cerebral haemorrhage was significantly higher on the 1st day of the disease than in patients with encephalomalacia. The difference was statistically significant with error probability of 0.05.


Subject(s)
Ammonia/blood , Cerebrovascular Disorders/blood , Adult , Aged , Cerebral Hemorrhage/blood , Encephalomalacia/blood , Humans , Middle Aged
3.
Neurol Neurochir Pol ; 11(6): 641-5, 1977.
Article in Polish | MEDLINE | ID: mdl-600344

ABSTRACT

The authors determined the activity of lipoprotein lipase in the blood and cerebrospinal fluid in 25 patients with exacerbation of multiple sclerosis and in 20 controls. A significant decrease in the activity of the enzyme was found in blood of the patients, while only trace activity was detected in the cerebrospinal fluid in both groups. The significant decrease of lipoprotein lipase activity in blood of patients the with multiple sclerosis requires further investigations.


Subject(s)
Lipoprotein Lipase/metabolism , Multiple Sclerosis/enzymology , Acute Disease , Adolescent , Adult , Female , Humans , Lipoprotein Lipase/blood , Lipoprotein Lipase/cerebrospinal fluid , Male , Multiple Sclerosis/blood , Multiple Sclerosis/cerebrospinal fluid
4.
Neurol Neurochir Pol ; 9(1): 89-93, 1975.
Article in Polish | MEDLINE | ID: mdl-1121358

ABSTRACT

In cases of thrombotic cerebral infarction the leucergic and thrombergic tests were done on the 2nd and 3d days of the disease and after 48 hours from the first dextran loading. Fleck's test tube method was used in the leucergy test. The proportion of agglutinated platelets was calculated from a smear stained by Papanicolau method. The results were processed statistically. An inhibitory effect of dextran on aggregation of white blood cells and platelets was observed in the blood of patients with cerebral infarction. The inhibitory effects of dextran was greater in relation to aggregation of platelets than white blood cells. However, in our investigations the effect of this agent on both processes was transient.


Subject(s)
Dextrans/pharmacology , Intracranial Embolism and Thrombosis/blood , Leukocytes/drug effects , Platelet Adhesiveness/drug effects , Aged , Brain/blood supply , Cell Aggregation/drug effects , Cerebrovascular Circulation , Depression, Chemical , Dextrans/therapeutic use , Humans , Infarction , Intracranial Embolism and Thrombosis/drug therapy , Middle Aged , Molecular Weight , Time Factors
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