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Eksp Klin Farmakol ; 62(3): 56-9, 1999.
Article in Russian | MEDLINE | ID: mdl-10439952

ABSTRACT

The specific activity of new drug forms (tablets, suppositories, ointments) of dubinal was studies on models of ischemic damage to the heart, toxic hepatitis, aseptic inflammation, damage to the skin and mucosa of the large intestine. It was found that the drug forms under study possessed a cardioprotective, hepatoprotective, anti-inflammatory, and wound-healing effect. This may serve as a prerequisite to their further clinical study.


Subject(s)
Antioxidants/administration & dosage , Butylated Hydroxytoluene/administration & dosage , Animals , Asepsis , Carbon Tetrachloride Poisoning/complications , Carbon Tetrachloride Poisoning/drug therapy , Chemical and Drug Induced Liver Injury/drug therapy , Chemical and Drug Induced Liver Injury/etiology , Disease Models, Animal , Drug Evaluation, Preclinical , Inflammation/chemically induced , Inflammation/drug therapy , Intestinal Diseases/drug therapy , Mice , Myocardial Infarction/drug therapy , Myocardial Infarction/etiology , Myocarditis/chemically induced , Myocarditis/drug therapy , Ointments , Rats , Suppositories , Tablets , Time Factors , Ulcer/drug therapy
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