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6.
Minerva Med ; 70(2): 97-111, 1979 Jan 14.
Article in Italian | MEDLINE | ID: mdl-219394

ABSTRACT

Recent data suggesting that oestrogens also encourage the onset of adenocarcinoma of the endometrium in man are reviewed. Emphasis is placed on the fact that this is most likely to occur when prolonged oestrogeni stimulation is not suitably opposed by progesterone. It is felt that the latter, or its synthetic homologues, should be employed in all long-standing cases of exogenous or endogenous hyperoestrogenism.


Subject(s)
Adenocarcinoma/etiology , Estrogens/adverse effects , Uterine Neoplasms/etiology , Adult , Animals , Breast Neoplasms/etiology , Chromosome Aberrations , Contraceptives, Oral, Hormonal/adverse effects , Estrogens/metabolism , Female , Humans , Japan , Menopause , Mice , Obesity/complications , Ovarian Neoplasms/metabolism , Parity , Progesterone/physiology , Rabbits , Rats , Receptors, Cell Surface , Registries , Risk , United States
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