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2.
5.
Neuropathol Appl Neurobiol ; 12(5): 477-82, 1986.
Article in English | MEDLINE | ID: mdl-3024051

ABSTRACT

In an electron microscopic study of brain biopsy material from a case with Creutzfeldt-Jakob disease intranuclear vacuoles containing membrano-vesicular structures were found. To our knowledge this finding has not been previously reported in human spongiform encephalopathies. It may represent a specific alteration associated with Creutzfeldt-Jakob disease, and suggests the possibility of nuclear infection.


Subject(s)
Creutzfeldt-Jakob Syndrome/pathology , Frontal Lobe/ultrastructure , Biopsy , Cell Nucleus/ultrastructure , Humans , Inclusion Bodies/ultrastructure , Male , Microscopy, Electron , Middle Aged , Vacuoles/ultrastructure
12.
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