ABSTRACT
We studied ten patients with Cystic fibrosis. The purposes of this study were to investigate the presence of gastroesophageal reflux and establish the probable association between gastroesophageal reflux and pulmonary and gastric involvement. All 10 patients underwent 24-hour esophageal pH recording, spirometry and gastric function. Abnormal reflux index was found in all these patients. Lung function was pathologic in the 3 older children. There were no relationship between the severity of the gastroesophageal reflux and the degree of pulmonary damage. No patient has gastric acid hypersecretion. Eight of 10 patients had steatorrhea. Our findings confirm the high frequence of gastroesophageal reflux in cystic fibrosis.
Subject(s)
Cystic Fibrosis/complications , Gastroesophageal Reflux/etiology , Lung/physiopathology , Stomach/physiopathology , Adolescent , Child , Cystic Fibrosis/physiopathology , Female , Gastric Acidity Determination , Gastroesophageal Reflux/physiopathology , Humans , Male , Respiratory Function TestsABSTRACT
Men with a background of unilateral torsion of testis (t.t.) show a greater percentage of infertility and changes in the spermiogram. Currently, the cause of contralateral testicle affectation remains unknown. With the aim of verify whether these changes are secondary to an immunological mechanism, the authors conducted experimental work in 3 groups of male rats, inducing a right t.t. over 24 hours, followed by detorsion and preservation of contorted testicle. Immunological response is determined through direct and indirect immunofluorescence reactions, including a brief description of the technique used. Positive reactions were obtained in both the spermatozoa's head and flagellum, more frequently in animals killed at 30 days and gradually decreasing in those killed at 60 and 90 days. The authors compare their results to other experimental works, and recommend to perform orchiectomy because of the damaging effect of the contorted testicle over the contralateral one.
