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Red cell exchange for rapid leukoreduction in adults with hyperleukocytosis and leukostasis.
Mack, Ethan A; Dougher, Meaghan C; Ginda, Ashley M; Cahill, Caitlin; Murter, Melissa; Schell, Kevin; Tanhehco, Yvette C; Bhoj, Vijay G; Fesnak, Andrew D; Siegel, Don L; Kambayashi, Taku; Aqui, Nicole A; O'Doherty, Una.
Blood ; 143(11): 1049-1054, 2024 Mar 14.
Article in English | MEDLINE | ID: mdl-38052031

ABSTRACT

ABSTRACT: We show that red cell exchange (RCE) treats hyperleukocytosis in acute leukemia. RCE provided similar leukoreduction to standard therapeutic leukoreduction and could be superior in patients with severe anemia or monocytic leukemias or when requiring rapid treatment.


Subject(s)
Leukemia, Monocytic, Acute , Leukemia, Myeloid, Acute , Leukostasis , Adult , Humans , Leukostasis/therapy , Leukemia, Myeloid, Acute/therapy , Leukemia, Monocytic, Acute/therapy , Acute Disease , Leukapheresis , Leukocytosis/therapy
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