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1.
Rev. Inst. Med. Trop. Säo Paulo ; 37(1): 75-9, jan.-fev. 1995. tab
Article in English | LILACS | ID: lil-154337

ABSTRACT

Aproxidamente 400 pacientes de hemodialise tratados em 5 diferentes unidades no Rio de Janeiro foram acompanhados durante 1 ano para presenca de marcadores virais de hepatite B e C. Durante o mesmo periodo, amostras foram tambem de 35 pacientes ambulatoriais de dialise peritonial continua (CAPD) e de 242 funcionarios das unidades. Dependendo da unidade em estudo foram detectadas prevalencias de anti-HCV variando de 47 por cento a 82 por cento (media 65 por cento ). Pacientes de prevalencia de anti-HCV em funcionarios foi de 2,9 por cento . Observamos uma taxa de ataque de hepatite C de 11,5 por cento por ano na populacao paciente de hemodialise anti-HCV negativo. Uma media de 9,4 por cento de pacientes de hemodialise eram portadores cronicos do virus da hepatite B (VHB) (taxa de 1.8 por cento a 20.4 por cento ), enquanto 48.9 por cento apresentaram marcadores de infeccao passada de HBV. A taxa de ataque de HBV foi de 4.5 por cento por ano (taxa de 0 por cento a 6 por cento ). Esses resultados indicam uma alarmante prevalencia alta anti-HCV em pacientes de hemodialise dessa regiao estudada.


Subject(s)
Humans , Renal Dialysis/adverse effects , Hepatitis C/transmission , Brazil , Follow-Up Studies , Hepatitis C/epidemiology , Risk Factors
2.
Rev Inst Med Trop Sao Paulo ; 37(1): 75-9, 1995.
Article in English | MEDLINE | ID: mdl-7569645

ABSTRACT

Nearly 400 hemodialysis patients treated at 5 different hemodialysis units in Rio de Janeiro were tested for one year for the presence of hepatitis C and B markers. During the same period, samples were also obtained from 35 continuous ambulatory peritoneal dialysis (CAPD) patients and from 242 health care workers. Depending on the hemodialysis unit studied, anti-HCV prevalence rates ranging from 47% to 82% (mean 65%) were detected. CAPD patients showed a lower prevalence of 17%. The prevalence of antibodies against hepatitis C virus (anti-HCV) among health care workers was 2.9%. We observed a hepatitis C attack rate of 11.5% per year in the anti-HCV-negative hemodialysis patient population. An average of 9.4% of the hemodialysis patients were chronic carriers of hepatitis B virus (HBV) (range 1.8% - 20.4%), while 48.9% showed markers of previous HBV infection. The HBV attack rate was 4.5% per year (range 0% - 6%). These results indicate an alarming high prevalence of anti-HCV among hemodialysis patients of this studied region.


Subject(s)
Hepatitis B/epidemiology , Hepatitis C/epidemiology , Renal Dialysis , Brazil/epidemiology , Hepatitis B/diagnosis , Hepatitis C/diagnosis , Humans , Peritoneal Dialysis, Continuous Ambulatory , Prevalence , Risk Factors
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