ABSTRACT
Post-irradiation cerebral pathologies may appear in various forms from localized radiation necrosis to a plurifocal type or from local to diffuse vasculopathies. Contrary to the current prevalent opinion, these lesions are not rare in children since young nerve tissue is particularly sensitive to ionizing radiation. Given the seriousness of some of these lesions, the authors recommend careful evaluation of the risk involved in relation to the real necessity of administering irradiation therapy in childhood.
Subject(s)
Brain Diseases/etiology , Radiation Injuries , Astrocytoma/diagnostic imaging , Astrocytoma/radiotherapy , Brain Diseases/diagnosis , Brain Diseases/diagnostic imaging , Brain Neoplasms/diagnostic imaging , Brain Neoplasms/radiotherapy , Cerebral Angiography , Child , Child, Preschool , Female , Humans , Magnetic Resonance Spectroscopy , Male , Meningeal Neoplasms/diagnosis , Meningeal Neoplasms/diagnostic imaging , Meningeal Neoplasms/radiotherapy , Meningioma/diagnosis , Meningioma/diagnostic imaging , Meningioma/radiotherapy , Necrosis , Tomography, X-Ray ComputedABSTRACT
Malignant exophthalmos is often not resolvable using only medical or radiation therapy. The pressure on the optic nerve which is generally associated with it evolves rapidly in many cases towards optic atrophy and subsequently loss of vision. Only surgical treatment offers any guarantee of success and of the various techniques proposed, subfrontal orbital decompression seems clearly the more effective, in that it makes for an optimal alleviation of pressure in the optic pathways. The Authors describe their technique, a variation on the original approach, and report the results achieved with it.
Subject(s)
Exophthalmos/surgery , Graves Disease/surgery , Orbit/surgery , Adult , Exophthalmos/etiology , Female , Graves Disease/drug therapy , Humans , MaleABSTRACT
Trigeminal neurinomas, unlike those of the acoustic nerve or of other cranial nerves, are relatively frequent in adolescence, making up 10% of the total. Two cases are described, bringing the number of reports in the world literature up to 13. The clinical, radiological and surgical data on these tumors are analyzed, and some particular aspects present in adolescence are pointed out.