ABSTRACT
We present the case of a 79-year-old woman who had received a diagnosis of Crohn's disease 3 years previously and who developed a mucosa-associated lymphoid tissue (MALT) lymphoma of the right colon while undergoing treatment with mesalazine. The patient had not received immunosuppressive drugs or infliximab. The possible association between Crohn's disease and the development of intestinal lymphomas is analyzed. The incidence, pathogenic mechanisms, diagnostic strategy, treatment and prognosis of these neoplasms are described, mainly with reference to MALT lymphomas of the colon.
Subject(s)
Colonic Neoplasms/complications , Crohn Disease/complications , Lymphoma, B-Cell, Marginal Zone/complications , Aged , Anti-Inflammatory Agents, Non-Steroidal/therapeutic use , Colonic Neoplasms/diagnosis , Crohn Disease/drug therapy , Female , Humans , Lymphoma, B-Cell, Marginal Zone/diagnosis , Mesalamine/therapeutic useABSTRACT
Se presenta el caso de una mujer de 79 años diagnosticada hacía 3 años de enfermedad de Crohn del colon, que desarrolló un linfoma tipo MALT de colon derecho estando en tratamiento con mesalazina y no habiendo recibido previamente fármacos inmunodepresores ni infliximab. Se analiza la posible asociación entre la enfermedad de Crohn y el desarrollo de linfomas intestinales: incidencia, mecanismos patogénicos, estrategia diagnóstica, tratamiento y pronóstico de esta neoplasia, haciendo alusión fundamentalmente al linfoma MALT de colon
We present the case of a 79-year-old woman who had received a diagnosis of Crohn's disease 3 years previously and who developed a mucosa-associated lymphoid tissue (MALT) lymphoma of the right colon while undergoing treatment with mesalazine. The patient had not received immunosuppressive drugs or infliximab. The possible association between Crohn's disease and the development of intestinal lymphomas is analyzed. The incidence, pathogenic mechanisms, diagnostic strategy, treatment and prognosis of these neoplasms are described, mainly with reference to MALT lymphomas of the colon
