Prevalencia de obesidad y de factores de riesgo cardiovascular en una población de pacientes pediátricos con diabetes tipo 1 / Prevalence of obesity and cardiovascular risk factors in a group of paediatric patients with type 1 diabetes

Objetivo: Se pretende establecer la prevalencia de sobrepeso-obesidad y síndrome metabólico en un grupo de pacientes pediátricos con diabetes tipo 1 (DM1) y determinar las repercusiones en el perfil lipoproteico y el control metabólico. Métodos: Se recoge a 115 pacientes (5-16 años) con DM1 e insulinoterapia intensiva. Se miden el peso, la talla, el índice de masa corporal (IMC), el perímetro abdominal (PA), la tensión arterial (TA), la hemoglobina glucosilada (HbA1c), el colesterol total (CT), el colesterol HDL (cHDL), el colesterol LDL (cLDL) y los triglicéridos (TG). Los resultados se estratifican por sexo y edad (< 11 años y ≥ 11 años). Resultados: Se obtiene una prevalencia de sobrepeso y obesidad (según valores de referencia de Hernández) del 28,69 y el 18,26%, respectivamente, con predominio femenino en ambos casos. La prevalencia de síndrome metabólico (según criterios de la Internacional Diabetes Federation) es del 3,22%. El 3,47% muesta PA > del percentil 90 para edad y sexo y el 2,6% TA sistólica ≥ 130mmHg y/o TA diastólica ≥ 85mmHg. El 4,34% muestra cHDL < 40mg/dl y el 2,6% TG ≥ 150mg/dl. Los pacientes con obesidad presentan niveles significativamente más bajos de cHDL y significativamente más altos de cLDL. No existen diferencias significativas en la HbA1c entre los pacientes con sobrepeso-obesidad y el resto. Conclusiones: Aunque el sobrepeso y la obesidad son frecuentes en los pacientes pediátricos con DM1, la prevalencia de síndrome metabólico y de factores de riesgo cardiovascular es más baja que en pacientes adultos. No obstante, el grupo de niños diabéticos con obesidad muestra un perfil lipoproteico de riesgo cardiovascular (AU)

Objective: To establish the prevalence of overweight-obesity and metabolic syndrome in a group of paediatric patients with type 1 diabetes (DM1), and to determine the effects on the lipoprotein profile and metabolic control. Methods: A group of 115 patients (5-16 years) with DM1, and on intensive insulin therapy was studied. Weight, height, body mass index (BMI), waist circumference (WC), blood pressure(BP), glycosylated haemoglobin (HbA1c), total cholesterol (TC), HDL-cholesterol (HDL-c), LDL cholesterol (LDL-c) and triglycerides (TG) were measured. The results were stratified by sexand age (< 11 years and≥11 years).Results: The prevalence of overweight and obesity (according to Hernández’s reference values) was 28.69% and 18.26%, respectively, with female predominance in both cases. The prevalence of metabolic syndrome (according to the International Diabetes Federation criteria) was 3.22%. 3.47% The WC adjusted for age and sex was > 90th percentile in 3.47% of cases, and 2.6% had a systolic BP≥130 mmHg and/or a diastolic BP≥85 mmHg. An HDL-c < 40 mg/dl was seen in 4.34%, and 2.6% had TG≥150 mg/dl. Obese patients had lower HDL-c levels and higher LDL-c levels than non-obese subjects. There were no significant differences in HbA1c between patients with overweight-obesity and the rest. Conclusions: Overweight and obesity are common in paediatric patients with DM1. Nevertheless, the prevalence of metabolic syndrome and cardiovascular risk factors is lower than in adult patients. The group of diabetic children with obesity had a lipoprotein profile of cardiovascular risk (AU)

[Prevalence of obesity and cardiovascular risk factors in a group of paediatric patients with type 1 diabetes]. / Prevalencia de obesidad y de factores de riesgo cardiovascular en una población de pacientes pediátricos con diabetes tipo 1.

OBJECTIVE: To establish the prevalence of overweight-obesity and metabolic syndrome in a group of paediatric patients with type 1 diabetes (DM1), and to determine the effects on the lipoprotein profile and metabolic control. METHODS: A group of 115 patients (5-16 years) with DM1, and on intensive insulin therapy was studied. Weight, height, body mass index (BMI), waist circumference (WC), blood pressure (BP), glycosylated haemoglobin (HbA1c), total cholesterol (TC), HDL-cholesterol (HDL-c), LDL-cholesterol (LDL-c) and triglycerides (TG) were measured. The results were stratified by sex and age (< 11 years and ≥ 11 years). RESULTS: The prevalence of overweight and obesity (according to Hernández's reference values) was 28.69% and 18.26%, respectively, with female predominance in both cases. The prevalence of metabolic syndrome (according to the International Diabetes Federation criteria) was 3.22%. 3.47% The WC adjusted for age and sex was > 90th percentile in 3.47% of cases, and 2.6% had a systolic BP ≥ 130 mmHg and/or a diastolic BP ≥ 85 mmHg. An HDL-c < 40 mg/dl was seen in 4.34%, and 2.6% had TG ≥ 150 mg/dl. Obese patients had lower HDL-c levels and higher LDL-c levels than non-obese subjects. There were no significant differences in HbA1c between patients with overweight-obesity and the rest. CONCLUSIONS: Overweight and obesity are common in paediatric patients with DM1. Nevertheless, the prevalence of metabolic syndrome and cardiovascular risk factors is lower than in adult patients. The group of diabetic children with obesity had a lipoprotein profile of cardiovascular risk.