ABSTRACT
We report a case of bilateral smooth muscle tumors (SMT) involving the adrenal glands in an 11-year-old female with acquired immunodeficiency syndrome (AIDS). The SMT of the right adrenal gland extended into the inferior vena cava, producing a tumor thrombus.
Subject(s)
Acquired Immunodeficiency Syndrome/complications , Adrenal Gland Neoplasms/diagnosis , Smooth Muscle Tumor/diagnosis , Adrenal Gland Neoplasms/complications , Child , Fatal Outcome , Female , Follow-Up Studies , Humans , Magnetic Resonance Imaging , Neoplasm Invasiveness , Phlebography , Smooth Muscle Tumor/complications , Tomography, X-Ray Computed , Vena Cava, Inferior/diagnostic imagingABSTRACT
Immunohistochemical staining for the 75-kDa, low-affinity nerve growth factor receptor (p75NGFR), within the cuneate nucleus (CN) of the adult rat revealed that this receptor is concentrated rostrocaudally in the middle CN (approximately 0.2-0.9 mm caudal to the obex), corresponding to that portion of the CN receiving densest projections of cutaneous primary afferent terminals. Furthermore, dense patches of p75NGFR-like immunoreactivity appear to correspond to the 'blotches' of cytochrome-oxidase activity observed in the middle region of the CN. This close correspondence between the localization pattern of p75NGFR in the CN and its functional organization suggests an important role for trophic factors in the CN's development and/or maintenance.
