1.
Vopr Virusol
; 32(4): 413-9, 1987.
Article
in Russian
| MEDLINE
| ID: mdl-3318131
ABSTRACT
The results of the authors' own studies and data from the literature attesting to an important role of proteolytic mechanisms in influenza virus physiology and the development of the infectious process are summarized. The etiotropic and pathogenetic effectiveness of proteolysis inhibitors in influenza was demonstrated experimentally and clinically. Data are presented on the immunostimulating and prophylactic effect of a proteolysis inhibitor, E-aminocaproic acid. It is concluded that the use of proteolysis inhibitors in viral infections holds good promise.
Subject(s)
Antiviral Agents , Influenza, Human/etiology , Orthomyxoviridae/pathogenicity , Peptide Hydrolases/metabolism , Protease Inhibitors/therapeutic use , Animals , Humans , Influenza, Human/microbiology , Mice , Orthomyxoviridae/drug effects , Orthomyxoviridae/enzymology , Virulence/drug effects , Virus Cultivation
2.
Med Radiol (Mosk)
; 20(9): 68-70, 1975 Sep.
Article
in Russian
| MEDLINE
| ID: mdl-1196055