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1.
J Neurointerv Surg ; 7(6): e22, 2015 Jun.
Article in English | MEDLINE | ID: mdl-24847090

ABSTRACT

A 67-year-old man with medically refractory vertebrobasilar insufficiency and short segment occlusions of the intracranial vertebral arteries was treated with angioplasty and stent placement. Fifteen hours after the procedure the patient developed symptoms of posterior fossa ischemia and repeat angiography showed thrombus formation within the stent which was treated with thrombolytic and aggressive antiplatelet therapy. Angiography revealed lysis of the clot, but concerns regarding the mechanism of the thrombotic phenomenon prompted frequency-domain optical coherence tomography (FDOCT) assessment. FDOCT provided excellent visualization of the stent and vessel wall interactions, as well as excluding residual flow-limiting stenosis, obviating the need for further intervention. The potential utility of FDOCT in the evaluation of intracranial atherosclerotic disease and additional intracranial applications are discussed.

2.
BMJ Case Rep ; 20142014 May 16.
Article in English | MEDLINE | ID: mdl-24835808

ABSTRACT

A 67-year-old man with medically refractory vertebrobasilar insufficiency and short segment occlusions of the intracranial vertebral arteries was treated with angioplasty and stent placement. Fifteen hours after the procedure the patient developed symptoms of posterior fossa ischemia and repeat angiography showed thrombus formation within the stent which was treated with thrombolytic and aggressive antiplatelet therapy. Angiography revealed lysis of the clot, but concerns regarding the mechanism of the thrombotic phenomenon prompted frequency-domain optical coherence tomography (FDOCT) assessment. FDOCT provided excellent visualization of the stent and vessel wall interactions, as well as excluding residual flow-limiting stenosis, obviating the need for further intervention. The potential utility of FDOCT in the evaluation of intracranial atherosclerotic disease and additional intracranial applications are discussed.


Subject(s)
Brain/pathology , Postoperative Complications/pathology , Stents , Thrombosis/pathology , Tomography, Optical Coherence/methods , Vertebral Artery/pathology , Vertebrobasilar Insufficiency/surgery , Aged , Angioplasty/methods , Atherosclerosis/pathology , Brain/blood supply , Cerebral Angiography , Fibrinolytic Agents/therapeutic use , Humans , Male , Thrombosis/therapy , Vertebral Artery/surgery
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