ABSTRACT
Protein C is a hepatic vitamin K-dependent protein which on activation, inhibits activated factor V and VIII and involves fibrinolytic activity. Protein C deficiency is associated with increased risk of thromboembolic complications. The article presents a family with hereditary protein C deficiency and discusses information concerning and follow-up of the family members.
Subject(s)
Protein C Deficiency , Thrombosis/genetics , Adult , Female , Follow-Up Studies , Humans , Male , Osteocalcin/metabolism , Risk FactorsABSTRACT
In a retrospective study the frequency of infertility was estimated in women operated for perforated or non-perforated appendicitis before the age of 25. Of the 48 patients with simple perforation 19% were infertile, while this frequency was 31% in 16 patients with Douglas abscess. In the control group of 58 patients 12% could not have children. It is concluded that it is unlikely that appendicitis with perforation will cause infertility unless there is a Douglas abscess.
