ABSTRACT
The regional-development of heterotopic bone around the hip and the influence of postoperative prophylaxis with antiinflammatory drugs were studied in 66 patients treated with 74 noncemented, porous-coated total hip arthroplasties (THA) using the McFarland approach. Thirty patients (34 hips) were treated with antiinflammatory drugs during the early postoperative period. Heterotopic bone developed in two different regions: central, around the neck of the femoral component, and lateral to the greater trochanter of the femur. Central ossifications were recorded in 53% of the hips and appeared significantly less frequently in patients postoperatively treated with antiinflammatory drugs. Lateral ossifications were recorded in 71% of the hips, and no significant prophylactic effect was found for postoperative antiinflammatory treatment. In response to the McFarland approach in THA, heterotopic ossifications may appear both centrally around the neck of the femoral component and lateral to the trochanter in the substance of the medial gluteal muscle. The latter may be comparable to post-traumatic myositis ossificans.
Subject(s)
Hip Prosthesis , Ossification, Heterotopic/diagnostic imaging , Postoperative Complications/diagnostic imaging , Adolescent , Adult , Aged , Anti-Inflammatory Agents, Non-Steroidal/therapeutic use , Female , Humans , Incidence , Male , Middle Aged , Ossification, Heterotopic/epidemiology , Ossification, Heterotopic/prevention & control , RadiographyABSTRACT
Complex dislocation of the little finger metacarpophalangeal joint is very rare. In the English literature, we have found only ten published cases. The condition usually requires open reduction, and most authors advocate a dorsal incision. We report two additional cases, treated by the volar approach, which makes a direct access to the incarcerated structures possible.
Subject(s)
Finger Injuries , Joint Dislocations , Metacarpophalangeal Joint/injuries , Adult , Humans , Joint Dislocations/surgery , Male , Metacarpophalangeal Joint/surgerySubject(s)
Pain/etiology , Radial Nerve , Adult , Female , Humans , Male , Middle Aged , Nerve Compression Syndromes/diagnosis , Nerve Compression Syndromes/surgery , Radial Nerve/surgerySubject(s)
Hand , Tendons/surgery , Tissue Adhesions/surgery , Adolescent , Adult , Child , Child, Preschool , Female , Humans , Male , Middle Aged , Tendons/pathologySubject(s)
Knee Joint/physiopathology , Patella/physiopathology , Adolescent , Adult , Female , Humans , Knee Joint/surgery , Male , Patella/surgery , Syndrome , Synovial MembraneABSTRACT
Metronidazole (500 mg) was infused over 20 min. to five patients. At the end of the infusion blood samples were drawn at brief intervals. After subsequent metronidazole analysis the curve plotted for the elimination of the drug showed a bi-exponential profile. Mean peak serum concentrations reached 15 micrograms per ml. At the end of the distribution phase, which was 20 to 30 min. after the infusion, the concentrations had fallen to 10 micrograms per ml. A two-compartment model was used to calculate the kinetic parameters. The elimination half-life ranged from 4.7 to 15.8 hours, the total clearance from 43 to 193 ml per min., and the peripheral distribution volume from 41.5 to 79.11 1. The areas under the serum level curves exhibited a four-fold variation, due to differences in either metabolism or elimination rate.
Subject(s)
Metronidazole/metabolism , Adult , Aged , Female , Half-Life , Humans , Infusions, Parenteral , Kinetics , Male , Metronidazole/administration & dosage , Middle Aged , Models, BiologicalSubject(s)
Tendon Injuries/surgery , Arm Injuries/surgery , Humans , Male , Middle Aged , Muscles/injuries , RuptureABSTRACT
Six cases of supracondylar fracture of the humerus in children were treated by closed reduction and percutaneous pinning with two Kirschner wires inserted laterally through the capitellum of the humerus. This treatment has the same advantages as the commonly used percutaneous pinning with crossed Kirschner wires inserted through the epicondyles of the humerus, and it further eliminates the risk of damaging the ulnar nerve by the insertion of the medial Kirschner wire.
