ABSTRACT
In 1998-1999 years the clinical and functional features of the stomachesophagus reflux disease (SERD) of 240 Chernobyl accident fighters and 310 patients of the group have been studied. Relative decreased acid production of the stomach has been observed in Chernobyl accident fighters. Clinic and endoscope pictures of different signs of SERD have been noted in 88.1% of patients with erosive and ulcerous injuries of the upper parts of the gastrointestinal tract, and SERD in 100% of cases combines with other pathology of organs of the gastrointestinal tract. For this group ill the complex examination and consulting help in conditions specialized gastroenterology of centers is necessary.
Subject(s)
Chernobyl Nuclear Accident , Gastroesophageal Reflux/etiology , Occupational Exposure/adverse effects , Case-Control Studies , Esophagoscopy , Gastroenteritis/diagnosis , Gastroenteritis/etiology , Gastroesophageal Reflux/diagnosis , Humans , Male , Middle Aged , Time Factors , UkraineABSTRACT
Healthy miners demonstrated increased relative levels of lysophosphatidyl choline and especially phosphatidyl inositol subunits. Metabolism of the latter could result in membrane accumulation of inositol triphosphate leading to cytoplasmic calcium increase and to bronchial smooth muscles contraction. Oral 20% choline chloride solution lowers bronchospasm in dust bronchitis patients with decreased serum subunits of phosphatidyl inositol and increased serum levels of phosphatidyl choline.
Subject(s)
Bronchitis/etiology , Bronchoconstriction , Dust/adverse effects , Mining , Occupational Diseases/etiology , Chronic Disease , Constriction, Pathologic/etiology , Humans , Occupational Diseases/epidemiology , Russia/epidemiologyABSTRACT
The study is designed to develop and to test the procedure of expert assessment of prophylactic activity of health care units at shop physician's departments in mines. Volume and quality of preventive work greatly influence workers' morbidity rates, hence the logistic support of the shop physician's service is of primary importance. It is emphasized that in order to improve prophylactic activity it is necessary to use all the available resources for enjoying conventional forms of shop's medical service.
