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Farmaco Sci ; 30(10): 789-801, 1975 Oct.
Article in English | MEDLINE | ID: mdl-241664

ABSTRACT

The synthesis and the pharmacological activities of 24 analogues of the alpha-adrenergic blocking drug, nicergoline (I b), are reported. The majority of the new compounds were found to be less active than (I b): the structure-activity relationships are presented and discussed.


Subject(s)
Adrenergic alpha-Antagonists/chemical synthesis , Crystallization , Esters , Methylation , Nicergoline/analogs & derivatives , Nicergoline/chemical synthesis
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