Patients receiving immunotherapy report it is effective as assessed by the rhinitis outcomes questionnaire (ROQ) in a private practice setting.

BACKGROUND: Outcomes measurement is a proficient method in determining the effectiveness of medical therapy. Currently, there are no easy-to-use and inexpensive questionnaires available to evaluate the effectiveness of immunotherapy by allergists in private practice. OBJECTIVE: To evaluate the effectiveness of immunotherapy in the treatment of patients with allergic rhinitis in a private practice setting using the rhinitis outcomes questionnaire (ROQ). METHODS: One hundred seventy-five patients were randomly chosen from three private practices nationwide. They were surveyed regarding global systemic problems and nasal, eye, and chest symptoms, as well as their medical treatment history. This questionnaire was administered twice in one sitting, with the first a recall of symptoms before immunotherapy treatment, and the second an evaluation of current symptoms. RESULTS: The data revealed that 81% of the patients believed immunotherapy worked, with 19% unsure. Patients experienced a 67% decrease in antibiotic use, a 68% decrease in emergency room visits, a 75% decrease in days lost from work or school, and a 79% decrease in hospital admissions. The average symptom score reduction with immunotherapy was 52%. CONCLUSIONS: This study demonstrates that the user-friendly ROQ can be effectively and inexpensively used in a private practice setting and that immunotherapy is effective in the treatment of allergic rhinitis.

Validation of the rhinitis outcomes questionnaire (ROQ).

BACKGROUND: Currently, there is no easy-to-use and comprehensive questionnaire that measures the effectiveness of treatment of rhinitis-related symptoms in a private practice setting. OBJECTIVE: To validate a brief, effective, self-administered rhinitis symptoms questionnaire that can easily be used in a private practice setting for tracking treatment outcomes. METHODS: One hundred seventy-five patients were randomly chosen from three private practices nationwide and were surveyed regarding systemic problems, nasal, eye, and chest symptoms, as well as medical treatment obtained. This survey was administered twice in one sitting with the first administration a recall of symptoms before immunotherapy, and the second administration an evaluation of current symptoms. Appropriate statistical methods were used to evaluate the validity, reliability, and responsiveness of the questionnaire presented. The validation of this instrument included content, statistical, construct, and predictive validity. RESULTS: Both the content and statistical validity were very good in that the questionnaire was easily understood and covered required domains. Construct validity revealed that the items were sensibly related to the domains that contained them and had less association with items from different domains. The reliability of the scales was very good (Cronbach's alpha = 0.80) to outstanding (Cronbach's alpha = 0.92). CONCLUSIONS: Functionality was established for the rhinitis outcomes questionnaire (ROQ) for use in a private practice setting. This allows private practice allergists to collect reliable data with the ROQ.

Analysis of meteorologic variables and seasonal aeroallergen pollen counts in Denver, Colorado.

BACKGROUND: The observation of low levels of weed pollens following a freeze and an early autumn snowfall in Denver, Colorado led to this analysis of meteorologic variables and pollen counts. OBJECTIVE: The purpose of this study was to examine, in depth, the relationship between observed pollen counts and a selection of independent meteorologic variables. METHODS: We prospectively studied in 1991 daily high and low temperature, relative humidity, precipitation, barometric pressure, percent sunshine, wind velocity and direction, tree, grass, and weed pollen, as well as dates of the first frost/freeze. Similar data were retrospectively analyzed for 1987-1990. RESULTS: Correlation coefficients for the prospective data were as high as .611 for high temperature and cottonwood and .718 for high temperature and maple (P < .001). High and low temperature showed strong correlations with the combined weed counts (.598 and .628, respectively, P < .001). CONCLUSIONS: Denver weed pollens appear impacted more by temperature and less by precipitation and humidity, while the converse is true for tree and grass pollen. However, weed pollen, especially sage, may appreciably rebound after freezing temperatures. While separate meteorologic variables may have high correlations with specific pollen counts in a given year, such effect is not consistent and varies from year to year.