Subject(s)
Purpura Fulminans/microbiology , Purpura Fulminans/therapy , Staphylococcal Infections/microbiology , Staphylococcal Infections/therapy , Biopsy , Diagnosis, Differential , Humans , Infant, Newborn , Male , Severity of Illness Index , Skin Transplantation , Staphylococcus aureus/isolation & purificationSubject(s)
Chemoradiotherapy/adverse effects , Immunocompromised Host , Lung Neoplasms/drug therapy , Neutropenia/chemically induced , Neutropenia/complications , Small Cell Lung Carcinoma/drug therapy , Tinea/etiology , Antifungal Agents/therapeutic use , Antineoplastic Combined Chemotherapy Protocols/administration & dosage , Antineoplastic Combined Chemotherapy Protocols/adverse effects , Female , Fluconazole/administration & dosage , Granuloma/drug therapy , Granuloma/microbiology , Granuloma/pathology , Humans , Itraconazole/administration & dosage , Lung Neoplasms/diagnosis , Middle Aged , Small Cell Lung Carcinoma/diagnosis , Tinea/immunology , Tinea/microbiology , Tinea/pathologySubject(s)
Airway Obstruction/surgery , Histiocytosis, Non-Langerhans-Cell/surgery , Laryngeal Diseases/surgery , Adult , Airway Obstruction/diagnostic imaging , Airway Obstruction/pathology , Female , Histiocytosis, Non-Langerhans-Cell/diagnostic imaging , Histiocytosis, Non-Langerhans-Cell/pathology , Humans , Laryngeal Diseases/diagnostic imaging , Laryngeal Diseases/pathology , Tomography, X-Ray ComputedABSTRACT
An unusual case of malignant cylindroma of the scalp arising in a 79-year-old white female with multiple cylindromatosis is presented. The tumor apparently arose from a cylindroma and had features of spiradenoma. Multiple cylindromatosis is an uncommon hereditary autosomal dominant disease, which is characterized by multiple skin adnexal tumors like cylindromas and trichoepitheliomas and occasional spiradenomas. Cylindroma is an uncommon benign tumor, which originates from skin appendages and is most commonly found on the scalp and face with a strong predilection for middle-aged and elderly females. Although cylindromas are usually benign neoplasms, carcinoma arising in such neoplasms is rare with only sporadic reports in literature. Her family history was negative for a similar disease. The patient's main concern was painful lesions over her right ear that interfered with wearing of her glasses. The clinical, histological immunohistochemical features, and treatment are presented along with a review of the literature.
Subject(s)
Carcinoma, Adenoid Cystic/pathology , Neoplasms, Multiple Primary/pathology , Scalp/pathology , Skin Neoplasms/pathology , Aged , Female , HumansABSTRACT
Basal cell carcinoma (BCC) is a rare disease in the pediatric population that usually presents in children with predisposing genetic conditions. It is often diagnosed on final pathology of an excisional biopsy, and the treatment may be delayed in younger populations because of a physician's low index of suspicion. Increased knowledge of BCC by pediatric caregivers would expedite definitive therapy for childhood BCC as well as any necessary evaluation by subspecialists for predisposing syndromes. We report 3 cases of BCC in pediatric patients and review the literature concerning BCC in children.
