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4.
Arch Dis Child ; 50(4): 318-20, 1975 Apr.
Article in English | MEDLINE | ID: mdl-1147671

ABSTRACT

A patient with idiopathic marrow hypoplasia associated with short stature and other anomalies (Fanconi's anaemia) is described: treatment with human growth hormone for one year did not accelerate his growth rate or significantly affect his anaemia: androgen treatment considerably improved both features. Endocrine studies suggest that though he had poor and insufficient production of endogenous growth hormone to insulin-induced hypoglycaemia, the major defect in this syndrome is determined more at the end-organ than at the pituitary or gonadal level.


Subject(s)
Anemia, Aplastic/complications , Fanconi Anemia/complications , Growth Disorders/complications , Growth Hormone/pharmacology , Blood Cell Count , Blood Transfusion , Body Height , Bone Marrow/pathology , Child , Chromosome Aberrations , Chromosome Disorders , Chromosomes, Human, 1-3 , Chromosomes, Human, 4-5 , Growth/drug effects , Growth Disorders/drug therapy , Growth Hormone/deficiency , Growth Hormone/therapeutic use , Humans , Male , Oxymetholone/therapeutic use , Pigmentation Disorders/etiology
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