[Dynamics of indicators of the "skin window" and change in body reactivity upon trauma]. / Dinamika pokazatelei "kozhnogo okna" i izmenenie reaktivnosti organizma pri travmakh.

The dynamics of indicators of the "skin window" was studied in 118 patients with fractures of the bones. The dynamics of changes of the indicators was found to correspond to severity of the trauma. The picture of dermocytograms in patients with complications was different as compared with that of patients without complications. The method can be used for the estimation of reactivity of the organism in clinical practice.

[The effect of the bone marrow fibroblasts from patients with malignant diseases of the blood system on the colony-forming capacity of granulomonocytic precursor cells]. / Vliianie fibroblastov kostnogo mozga bol'nykh zlokachestvennymi zabolevaniiami sistemy krovi na kolonieobrazuiushchuiu sposobnost' granulomonotsitarnykh kletok-predshestvennikov.

The inhibiting activity of bone marrow fibroblasts and their ability to sustain survival of granulocytic cell precursors have been studied in patients with chronic myelocytic leukemia, chronic lymphoproliferative disorders, acute leukemia, myelodysplastic syndrome. Fibroblast conditioned medium inhibits proliferation of granulomonocytic precursors stimulated by leucocyte feeder layer or leucocyte conditioned medium. The effect depends both on the presence of monocytes and the specificity of the disease. The inhibitory effect is related with long-ranged factors. Bone marrow fibroblasts are able to sustain survival of hemopoietic precursors via humoral and cell-cell mechanisms. The regulatory role of bone marrow fibroblasts in hemopoietic disorders is discussed.

[A method for evaluating a diagnostic inflammatory focus by using the "cold test"]. / Metod otsenki diagnosticheskogo ochaga vospaleniia s pomoshch'iu "kholodovogo testa".

Clinico-morphological test for the quantitative evaluation of exudative and cell response in the diagnostical inflammatory focus in various forms of human pathology is developed. The values in practically healthy persons are established. The possibilities of the test use for the prognosis of disease and the development of postoperative complications in patients with cold trauma are shown.

[Dynamics of indicators of dermocytograms and reparative capacity of the body in burns]. / Dinamika pokazatelei dermotsitogramm i reparativnye sposobnosti organizma u obozhzhennykh.

The investigation of dermocytograms by a modified method of the "skin window" in 101 patients with different square surfaces of deep burns has shown that the dynamics of mononuclear content is dependent on the injury degree. Lower parameters of mononuclear content in dermocytograms during the course of treatment correspond to the disturbance of reparative capacities of the organism in groups of patients with the complicated course of the disease. The "skin window" test can be used for the treatment since it shows the degree of the burn trauma dynamics and character of its course, facilitates the prognosis of complications.

[Plastic surgery using split skin flap in the primary surgical treatment of crural injuries]. / Plastika rasshcheplennym kozhnym loskutom pri pervichnoi khirurgicheskoi obrabotke povrezhdenii goleni.

An experience with skin plasty in 127 patients is described. Special attention is called to necessary excision of non-viable tissues in fractures of the skin bone and reapplication of the rejected skin.