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Gematol Transfuziol ; 35(1): 25-7, 1990 Jan.
Article in Russian | MEDLINE | ID: mdl-2328900

ABSTRACT

Cytogenetic and mitotic disorders were studied in 151 patients with acute non-lymphoblastic leukemia. A significant rise in the incidence of clonal disorders with predominant affection of chromosomes 5 and 7, and an increase in the percentage of cases with the presence of pathologic mitoses in hemopoietic cells have been recorded in patients who, due to their occupation, have been exposed to potentially mutagenic chemical substances.


Subject(s)
Air Pollutants, Occupational/adverse effects , Chemical Industry , Chromosome Aberrations/genetics , Chromosomes, Human, Pair 5/drug effects , Chromosomes, Human, Pair 7/drug effects , Leukemia, Myeloid, Acute/genetics , Mitosis/drug effects , Occupational Diseases/genetics , Humans , Leukemia, Myeloid, Acute/chemically induced , Occupational Diseases/chemically induced , USSR
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