[Outcome of acute renal failure in subjects with HIV living in Abidjan, Ivory Coast over the period 1st January 2014 to 31st December 2017]. / Profil évolutif de l'insuffisance rénale aiguë chez les personnes vivant avec le VIH à Abidjan, Côte d'Ivoire du 1er janvier 2014 au 31 décembre 2017.

In Ivory Coast, the prevalence of human immunodeficiency virus (HIV) infection is high. Any organ can be affected, in particular the kidney. Some studies conducted in Ivory Coast highlighted that opportunistic infections are a poor prognostic factors for acute renal failure (ARF). The purpose of this study was to investigate the other possible factors associated with ARF outcome among subjects with HIV infection. We conducted a retrospective analytical study, at the University Hospital Center of Yopougon over the period January 2014-December 2017. All patients over the age of 18 years with HIV infection associated with ARF were enrolled. The study included 73 patients, reflecting a rate of 24%. The average age of patients was 39.32 ± 10.50 years, ranging from 18 to 65 years. Sex ratio of 1.6 favoured women. Obesity (p=0.047; OR=8.72; CI (95%)=1.07-39.21) and CD4 count < 200/mm3 (p=0.000; OR=58.50; IC (95%)=10.31-55.12) were associated with poor prognosis of ARF. In Ivory Coast, the hospital prevalence of ARF in patients with HIV is high. Unfavorable outcome included death or chronicity. In addition to deep immunosuppression already known as a poor prognostic factor, this study showed that obesity is associated with unfavorable outcome of ARF in subjects with HIV.

[Uncontrolled hypertension in chronic kidney disease in patients from black Africa admitted in a renal unit: a retrospective analysis]. / Épidémiologie de l'hypertension artérielle non contrôlée au cours des maladies rénales chroniques chez des patients admis dans une unité de néphrologie d'Afrique noire : une étude rétrospective de 479 patients.

The incidence of uncontrolled hypertension (HTN+) in CKD in nephrology could reflect the quality of the management of the patients in a primary care setting. The aim of the present study was to identify factors associated with HTN+ in CKD in order to elaborate a prevention strategy for the health professionals. A retrospective analysis of 479 incidents patients has been performed from 2012/1st to 2012/12th. Sixty-two percent had CKD HTN+. Eighty percent were at stages 4 and 5. Mean value of SBP was 166.5±32 mmHg and 96±27.3 mmHg for DBP. Mean age was 48.2±14.6 years. Mean GFR was 17.4±17.1 mL/min and no difference found between groups (17.4±17.6 mL/min in CKD HTN+ versus 17.5±16.3 mL/min in CKD HTN-, P < 0.9). Alcohol consumption was more in CKD HTN+ as compared to CKD HTN-, but not different between groups (37.2% in CKD HTN+ versus 27.6% in CKD HTN-; P < 0.09). Patients who were taking antihypertensive drugs were significantly more in the CKD HTN- than CKD HTN+ (22% in CKD HT+ versus 41.1% in CKD HTN-; P < 0.0001). Factors associated with HTN+ in CKD were antihypertensive therapy (OR = 0.39; CI 0.20-0.75; P < 0.005); alcohol (OR = 2.19; CI 1.09-4.37; P < 0.02). BP was similar in HN and non-HN patients (173.0±26.9 mmHg versus 174.7±33.7 mmHg; P = 0.75). But kidney function was a little better in HN (16.9±17.7 mL/min and 20.95±18.5 mL/min; P < 0.1). Factors associated positively with HN/HTN+ were: history of HTN and age. Factors associated negatively with HN/HTN+ were: history of diabetes and CKD stage.