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1.
Eur J Obstet Gynecol Reprod Biol ; 299: 173-181, 2024 Mar 31.
Article in English | MEDLINE | ID: mdl-38878521

ABSTRACT

INTRODUCTION AND HYPOTHESIS: Vaginal mesh has been used for years to try to improve the results of pelvic organ prolapse surgery, but current evidence does not confirm this improvement and instead describes serious and frequent adverse events. CLINICAL CASE: 64-year-old patient with rectal extrusion of posterior vaginal mesh placed 8 years earlier, and persistent left ischiorectal fistula refractory to surgery. She required 5 surgeries, carried out jointly between gynecology and general surgery, to solve, firstly, the bilateral perianal abscess secondary to extrusion of the posterior vaginal mesh into the rectum and then the persistent left ischiorectal fistula, despite the removal of the material prosthetic. Finally, the fistula was solved by injection of platelet-rich plasma. CONCLUSIONS: Vaginal mesh complications often need a multidisciplinary approach, and treatment may require multiple approaches and more than one surgical procedure. In the case of a persistent fistula refractory to surgery, after removing the mesh, non-invasive regenerative therapies that promote vascular growth and tissue regeneration could be considered such as platelet-rich plasma.

2.
Article in English | LILACS-Express | LILACS | ID: biblio-1534157

ABSTRACT

Introduction: Hydatidiform mole is a type of gestational trophoblastic disease that results from the abnormal fertilization of an oocyte and causes nonspecific symptoms such as amenorrhea, metrorrhagia, and enlarged uterus. Although rare, its most characteristic symptoms include hyperemesis, early-onset pre-eclampsia, anemia, and respiratory distress. Case presentation: A 47-year-old Moroccan woman consulted the emergency department of the Hospital Clínico Universitario in Valladolid (Spain) after a month of persistent coughing and emesis. The patient reported epigastralgia and amenorrhoea for two months, as well as scant vaginal bleeding two days prior to consultation. Taking into account that the patient tested positive for pregnancy, that a heterogeneous intrauterine mass measuring 124x120mm was observed on transvaginal ultrasound, that no abnormal findings were reported on Doppler ultrasound, and that her serum ßhCG levels reached a value of 772.110 mIU/mL, a diagnosis of hydatidiform mole was suspected. Once informed about the possible therapeutic options, the patient decided to undergo a total hysterectomy, as she stated that she had already fulfilled her desire to be a mother. After the procedure, the patient's clinical condition improved, and the pathology report of the mass confirmed the diagnosis of partial hydatidiform mole. Conclusion: Early diagnosis of hydatidiform mole is paramount in order to provide adequate treatment and improve the prognosis of these patients. Therefore, despite its low incidence and non-specific clinical manifestations, it should be considered as a differential diagnosis for first-trimester metrorrhagia.


Introducción. La mola hidatiforme es un tipo de enfermedad trofoblástica gestacional que se presenta como resultado de la fertilización anormal de un ovocito y que ocasiona síntomas inespecíficos como amenorrea, metrorragia y aumento del tamaño del útero. Aunque infrecuentes, sus síntomas más característicos incluyen hiperémesis, preeclampsia de inicio temprano, anemia y distrés respiratorio. Presentación del caso. Mujer marroquí de 47 años que consultó al servicio de urgencias del Hospital Clínico Universitario de Valladolid debido a que había presentado tos y vómitos por un mes. La paciente refirió haber sufrido epigastralgia y amenorrea por dos meses, así como escaso sangrado vaginal en los últimos dos días. Teniendo en cuenta que la paciente dio positivo en una prueba de embarazo, que en la ecografía transvaginal se observó una masa intrauterina heterogénea de 124x120mm, que no se reportaron hallazgos anormales en la ecografía Doppler y que sus niveles séricos de ßhCG alcanzaron un valor de 772.110 mUI/mL, se sospechó un diagnóstico de mola hidatiforme. Una vez informada sobre las posibles alternativas terapéuticas, la paciente decidió someterse a una histerectomía total, pues refirió que ya había cumplido su deseo de ser madre. Luego de realizar procedimiento, la condición clínica de la paciente mejoró; además, el informe de patología de la masa permitió confirmar el diagnóstico de mola hidatiforme parcial. Conclusiones. El diagnóstico temprano de la mola hidatiforme es de gran importancia para ofrecer un tratamiento adecuado y, de esta forma, mejorar el pronóstico de estas pacientes. Por tanto, a pesar de su baja incidencia y sus manifestaciones clínicas inespecíficas, se debe considerar como diagnóstico diferencial de las metrorragias del primer trimestre.

3.
Metas enferm ; 20(9): 11-14, nov. 2017. graf, tab
Article in Spanish | IBECS | ID: ibc-168760

ABSTRACT

Objetivo: valorar la calidad de la dieta de los pacientes, conocer su influencia en la calidad seminal y planificar actividades para la modificación de hábitos dietéticos. Método: estudio descriptivo transversal de los hábitos dietéticos sobre 50 varones derivados a la Unidad de Reproducción Asistida, en la cual, junto a sus parejas, acudían para recibir tratamiento de fecundación in vitro (FIV). Se recogió la ingesta autorreportada de dos días no consecutivos. Se utilizó el programa Dietsource 3.0 para procesar la información dietética. En el análisis bivariante se empleó el coeficiente de correlación de Pearson y el de Spearman. Como valores de referencia se han utilizado las ingestas recomendadas para la población española. Resultados: más de la mitad de los varones presentó valores de ingesta calórica inferiores a las 3.000 kcal/d (mediana= 2.700,10). El consumo de carbohidratos fue inferior a la cantidad recomendada mientras que los lípidos, y sobre todo las proteínas, se ingirieron en exceso. Únicamente se encontró relación estadísticamente significativa (p= 0,025) entre la ingesta proteica (g/d) y el recuento de espermatozoides móviles (REM) (a valores de ingesta proteica altos, mayores recuentos de espermatozoides móviles). Conclusiones: los varones estudiados ingirieron una proporción mayor de proteínas y grasas de las recomendadas, siendo básicamente una dieta normo-hipocalórica, hiperproteica e hiperlipídica. Sin embargo, tan solo se halló relación entre la ingesta proteica y la cantidad de espermatozoides móviles en el laboratorio (REM). Se constató una amplia dispersión tanto en el recuento como en movilidad de los espermatozoides, seguramente determinada por la indicación de la FIV (AU)


Objective: to evaluate the quality of patient diet, to understand its influence on seminal quality, and to plan activities for the modification of dietary habits. Method: a descriptive transversal study of dietary habits on 50 men referred to the Assisted Reproductive Unit, which they attended with their partners in order to receive in vitro fertilization treatment. Their self-reported food intake was collected for two non-consecutive days. The Dietsource 3.0 program was used to process this diet information. Pearson and Spearman correlation coefficients were used for bivariate analysis. The reference values used were the recommended intakes for the Spanish population. Results: over half of men presented values of calorie intake < 3,000 kcal/day (median= 2,700.10). Carbohydrate intake was below the recommended level, while there was an excessive intake of lipids, and most of all of proteins. Statistically significant association (p= 0.025) was only found between protein intake (g/day) and motile sperm count (MSC): at high values of protein intake, higher motile sperm counts. Conclusions: the intake proportion of proteins and lipids in those men studied was above recommendations; their diet was basically normal or low-calorie, hyperproteic and hyperlipidic. However, the only association found was between protein intake and the motile sperm count (MSC) at the lab. A wide dispersion was confirmed, both in sperm count and motility, probably determined by the IVF indication (AU)


Subject(s)
Humans , Male , Eating/physiology , Semen Analysis , Food Quality , Feeding Behavior/physiology , Reproductive Techniques, Assisted/nursing , Fertilization in Vitro/methods , Healthy Lifestyle/physiology , Diet, Healthy , Statistics, Nonparametric , Fujita-Pearson Scale , Cross-Sectional Studies/methods , Energy Intake
4.
Rev. chil. obstet. ginecol ; 81(6): 496-501, dic. 2016. ilus, tab
Article in Spanish | LILACS | ID: biblio-844522

ABSTRACT

Antecedentes: La relación entre la longitud del segundo y cuarto dedo de las manos (ratio D2:D4) se ha relacionado con la exposición intrauterina a los andrógenos. Se define un patrón androgénico cuando la longitud del cuarto dedo es superior a la del segundo y el cociente es menor de 1. Este ratio se pone en relación con aspectos del desarrollo y la función reproductiva de los individuos, tales como la resistencia al ejercicio físico, el autismo, la concentración de espermatozoides o la esterilidad. Objetivo: Establecer asociación entre la ratio D2:D4 con la edad de la menarquia. Método: Estudio transversal descriptivo sobre una población no seleccionada de 188 mujeres. Se recogen las longitudes de los dedos con un calibre digital, desde una imagen en papel obtenida con un escáner. El análisis estadístico se realizó mediante el test de correlación de Pearson, considerando significativo un valor de p<0,05. Resultados: El análisis de correlación entre los parámetros morfométricos de las manos y la edad de la menarquia, presentó relación estadísticamente significativa y directamente proporcional con la longitud del cuarto dedo en ambos manos. Conclusión: Los resultados obtenidos indican una relación entre el perfil androgénico de la morfometría de las manos y el retraso de la menarquia. Este hecho constituye un inicio en la búsqueda de relaciones entre las características morfométricas de las manos y condiciones clínicas, que podrían estar influenciadas por la exposición androgénica durante el periodo fetal.


Background: The relationship between the length of the second and fourth fingers of the hands (ratio D2:D4) has been associated with intrauterine exposure to androgens. The androgenic pattern is defined when the length of the fourth finger is higher than the second, and the ratio is lower than 1. This ratio is set in relation to aspects of development and reproductive function of individuals, such as resistance to physical exercise, autism, sperm concentration or sterility. Aims: Find relationship between the ratio D2:D4 with age of menarche. Methods: Descriptive cross-sectional study in an unselected population of 188 women. The finger lengths with a digital caliper is collected from a paper image obtained by a scanner. Statistical analysis was perfomed using the Pearson correlation coefficient, with significant value p<0.05. Results: Correlation analysis between the morphometric parameters of the hands and the age of menarche, showed statistically significant and directly proportional to the length of the fourth finger on both hands relationship. Conclusion: The results indicate a relationship between the androgenic pattern morphometry hands and late menarche. This is a start in the search for relationships between the morphometric characteristics of the hands and clinical conditions that might be influenced by androgen exposure during fetal period.


Subject(s)
Humans , Female , Adult , Middle Aged , Young Adult , Hand/anatomy & histology , Menarche , Cross-Sectional Studies , Fingers/anatomy & histology
5.
Arch Gynecol Obstet ; 293(2): 311-6, 2016 Feb.
Article in English | MEDLINE | ID: mdl-26066659

ABSTRACT

PURPOSE: To analyse the validity of ultrasonography in predicting the outcomes of labour induction, compared with Bishop score (BS), and to design a predictive model including ultrasound and clinical variables. METHODS: In this prospective, observational study of 151 women who underwent induction of labour, an endovaginal ultrasound was performed to determine cervical length (CL), the wedging pattern and the presence of dilatation and funnel. Foetal head-perineum distance (FHPD) was measured by transperineal ultrasound. Vaginal examination was performed to calculate BS and to determine whether cervical ripening was needed. The outcome variable was the method of delivery. RESULTS: Caesarean section was performed in 30.5 % of cases. CL (26.1 vs. 31.4) and FHPD (44.7 vs. 51.3) were lower in the vaginal delivery group. The area under the curve obtained for FHPD (0.734) was greatest, followed by CL (0.663) and BS (0.678). The proposed model resulted in correct predictions in 82.8 % of cases, with 15 % false positives. CONCLUSIONS: The FHPD and the CL are useful in predicting the result of the induction labour comparable to Bishop score. Using ultrasound scan is significantly better tolerated than vaginal exam. The predictive model selects women who undergo induction having a risk of caesarean section equivalent to spontaneous delivery.


Subject(s)
Cervix Uteri/diagnostic imaging , Cesarean Section/statistics & numerical data , Delivery, Obstetric/methods , Labor, Induced/methods , Pregnancy Outcome , Ultrasonography, Prenatal/methods , Adult , Cervical Ripening/physiology , Delivery, Obstetric/statistics & numerical data , Female , Fetus , Head/diagnostic imaging , Humans , Perineum , Predictive Value of Tests , Pregnancy , Prospective Studies , Reproducibility of Results , Sensitivity and Specificity , Treatment Outcome , Ultrasonography, Prenatal/statistics & numerical data
6.
Prog. obstet. ginecol. (Ed. impr.) ; 54(11): 575-580, nov. 2011. tab
Article in Spanish | IBECS | ID: ibc-91173

ABSTRACT

Objetivo. Comparar los resultados perinatales de gestantes mayores de 35 años con un grupo control (< 35 años). Diseño. Estudio de cohortes históricas. Lugar. Valladolid (España). Método: análisis univariante y estimación de RR. Variables estudiadas. relativas a la epidemiología, desarrollo del embarazo y resultados perinatales. Resultados. Se analizaron 1455 partos (355 correspondientes al grupo de estudio: 24,39%). Las gestantes de mayor edad presentaron más patología asociada al embarazo (29,2 vs 15,8%, p<0,001) como diabetes gestacional (6.2%, p<0.0029), metrorragia del primer trimestre (5.6%, p<0.01), y amenaza de parto prematuro (3.9%, P<0.007). Los estados hipertensivos del embarazo aunque fueron también más frecuentes no demostraron significación estadística. Se requirió inducción médica del parto con mayor frecuencia en el grupo de estudio (RR=1.42; CI 95%:1.08-1.87). En el 47% de las gestantes nulíparas de edad avanzada se indicó una cesárea (RR=1.63; CI 95%: 1.24-2.15). La tasa de mortalidad perinatal en el grupo de estudio fue 16.5‰ vs 2.77‰ en el grupo control. La morbilidad materna también fue superior en el grupo de edad avanzada (RR 5.98; CI 95% 1.35-26.54), fundamentalmente por complicaciones hemorrágicas. Conclusiones. la edad materna avanzada se asocia con mayor frecuencia a patología gestacional y mayor incidencia de inducciones médicas del parto y tasa de cesáreas, especialmente en nulíparas. Todo ello repercute en la morbimortalidad materna y fetal, siendo un grupo poblacional de riesgo obstétrico que requiere una atención prenatal adecuada y trasciende el ámbito de la planificación sanitaria, dado el porcentaje de gestantes de edad avanzada en nuestro medio (AU)


Objective. To compare perinatal outcomes in women aged 35 years or over with those in a control group aged less than 35 years. Design. Historical cohort study. Setting. Valladolid (Spain). Methods. Univariate analysis was performed with estimation of relative risks (RR). Variables related to epidemiology, pregnancy course and perinatal outcomes were analyzed. Results. A total of 1,455 deliveries were analyzed, of which 355 involved women aged 35 years or over (24.39%). Older women more frequently showed pregnancy-associated disorders (29.2 vs 15.8%, p<0.001): gestational diabetes (6.2%, p<0.0029), first-trimester metrorrhagia (5.6%, p<0.01), and risk of preterm birth (3.9%, P<0.007); pregnancy-induced hypertension was also more frequent in this group but this difference was not statistically significant. Induction of labor was more frequently required in the older group (RR=1.42; 95% CI:1.08-1.87). Cesarean section was required in 47% of older nulliparous women (RR=1.63; 95% CI: 1.24-2.15). The overall perinatal mortality rate in older patients was 16.5‰, compared with 2.77‰ in the control group. Maternal morbidity was higher in the group of older patients (RR 5.98; 95% CI 1.35-26.54) and mainly consisted of hemorrhagic complications. Conclusions. Advanced maternal age is associated with a higher frequency of pregnancy-related disorders and a greater incidence of medically-induced delivery and cesarean sections, especially in primiparous mothers. Age therefore influences maternal and fetal morbidity and mortality. Consequently, these women constitute an obstetric risk population requiring special attention which, given the number of older pregnant women, goes beyond the scope of health provisions in our environment (AU)


Subject(s)
Humans , Female , Pregnancy , Adult , Maternal Age , Risk Factors , Cesarean Section/methods , Diabetes, Gestational/epidemiology , Cohort Studies , Metrorrhagia/complications , Metrorrhagia/diagnosis , Mortality
7.
Prog. obstet. ginecol. (Ed. impr.) ; 53(8): 324-327, ago. 2010. tab
Article in Spanish | IBECS | ID: ibc-81460

ABSTRACT

El polihidramnios, con una incidencia de 1/200 gestaciones, se define como el aumento de la cantidad de líquido amniótico y se asocia a un aumento de la patología perinatal. Se debe a una alteración del equilibrio que existe entre la producción y la eliminación del fluido. Se diagnostica mediante estudio ecográfico y se determina por métodos semicuantitativos. Durante el embarazo se puede realizar un estudio etiológico. El tratamiento va encaminado a disminuir el riesgo de complicaciones debidas a la hiperdistensión uterina, sobre todo el parto prematuro, y a adecuar la atención a los recién nacidos. Presentamos un caso de polihidramnios grave tratado mediante amniodrenaje repetido, producido por un seudohipoaldosteronismo, causa infrecuente de hidramnios y difícil de diagnosticar mediante el estudio prenatal habitual (AU)


The polyhydramnios, with an incidence of 1/200 pregnancies, defined as the increase in the amount of amniotic fluid, is associated with an increase in perinatal pathology. It is due to disruption of the equilibrium that exists between the production and removal of the fluid. It is diagnosed by ultrasound and is determined by semi-quantitative methods. During pregnancy can be An aetiological study may be made during pregnancy. The treatment is aimed at reducing the risk of complications due to uterine overdistensión, mainly pre-term birth, and appropriate care of the newborn. We report a case of severe polyhydramnios treated by repeated amniodrainage, produced by a pseudo-hypoaldosteronism, a rare cause, and difficult to diagnose by routine prenatal study (AU)


Subject(s)
Humans , Female , Pregnancy , Adult , Polyhydramnios/diagnosis , Polyhydramnios/therapy , Hypoaldosteronism/complications , Hypoaldosteronism/diagnosis , Betamethasone/therapeutic use , Indomethacin/therapeutic use , Biopsy, Needle , Ritodrine/therapeutic use , Hypoaldosteronism/etiology , Hypoaldosteronism/therapy , Risk Factors , Pregnancy Complications/physiopathology , Pregnancy Complications , Fetal Membranes, Premature Rupture/diagnosis
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