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1.
Arch Pediatr ; 21(6): 628-31, 2014 Jun.
Article in French | MEDLINE | ID: mdl-24768073

ABSTRACT

Infant botulism is a rare neuroparalytic disease caused by the neurotoxin of Clostridium botulinum. Initial clinical features are constipation, poor feeding, descending hypotonia, drooling, irritability, weak crying and cranial nerve dysfunctions. We describe the clinical progression and the epidemiological investigation carried out in a 3-month-old infant. Better knowledge of the disease should allow faster diagnosis and adequate management. We emphasize the risks associated with honey exposure in children less than one year old and that honey should not be fed to infants under 12 months of age.


Subject(s)
Botulism/diagnosis , Honey/microbiology , Botulism/etiology , Female , Honey/adverse effects , Humans , Infant
2.
J Endocrinol Invest ; 28(11): 1024-8, 2005 Dec.
Article in English | MEDLINE | ID: mdl-16483183

ABSTRACT

This is the first report of intense fluorodeoxyglucose positron emission tomography (FDG-PET) uptake secondary to thymic hyperplasia during follow-up for thyroid carcinoma. A 36-yr-old woman underwent thyroidectomy for a papillary carcinoma measuring 4 cm in diameter. After two doses of radioiodine, thyroglobulin (Tg) remained detectable following recombinant human TSH (rhTSH) stimulation. A whole body scan (WBS) was negative. On computed tomography (CT) scan, a slightly lobulated thymus was visualized. PET scan showed intense thymic uptake. Following resection, anatomo-pathological analysis showed homogenous hyperplastic thymic gland without neoplastic cells. Two months later, under levothyroxin (L-T4) substitution, Tg was no longer detectable and PET scanning did not show any 18-FDG uptake. This observation suggests that thymic FDG uptake does not necessarily herald recurrence of thyroid carcinoma and must be interpreted with caution in such a setting. Other conditions associated with abnormal uptake by hyperplastic thymus must also be envisaged.


Subject(s)
Carcinoma, Papillary/diagnostic imaging , Fluorodeoxyglucose F18 , Neoplasm Recurrence, Local/pathology , Radiopharmaceuticals , Thymus Gland/diagnostic imaging , Thyroid Neoplasms/diagnostic imaging , Adult , Carcinoma, Papillary/blood , Carcinoma, Papillary/surgery , Female , Humans , Iodine Radioisotopes , Thyroglobulin/blood , Thyroid Neoplasms/blood , Thyroid Neoplasms/surgery , Thyroidectomy , Thyrotropin/pharmacology , Thyroxine/pharmacology , Tomography, Emission-Computed
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