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2.
J Clin Endocrinol Metab ; 85(11): 3964-7, 2000 Nov.
Article in English | MEDLINE | ID: mdl-11095414

ABSTRACT

We describe a case of metastasizing congenital adrenocortical carcinoma and a follow-up of 3 1/2 yr. Treatment with surgery and mitotane was associated with multiple complications. The patient was in remission at 3 1/2 yr. Because of the rarity of this condition, we discuss step-by-step problems encountered during management.


Subject(s)
Adrenal Cortex Neoplasms/surgery , Adrenal Cortex Neoplasms/congenital , Adrenal Cortex Neoplasms/drug therapy , Adrenal Cortex Neoplasms/pathology , Antineoplastic Agents, Hormonal/therapeutic use , Combined Modality Therapy , Follow-Up Studies , Humans , Hydrocortisone/therapeutic use , Infant, Newborn , Male , Mitotane/therapeutic use , Neoplasm Metastasis , Postoperative Complications , Time Factors , Tomography, X-Ray Computed
3.
J Pediatr ; 137(2): 260-2, 2000 Aug.
Article in English | MEDLINE | ID: mdl-10931423

ABSTRACT

We describe a child who has central diabetes insipidus associated with congenital nasal pyriform aperture stenosis without any apparent anterior pituitary dysfunction. This association further strengthens the concept that congenital nasal pyriform aperture stenosis may be a microform of holoprosencephaly.


Subject(s)
Abnormalities, Multiple , Diabetes Insipidus , Nasal Cavity/abnormalities , Nasal Obstruction/congenital , Abnormalities, Multiple/diagnosis , Abnormalities, Multiple/genetics , Diabetes Insipidus/genetics , Female , Holoprosencephaly/genetics , Humans , Infant, Newborn , Nasal Obstruction/diagnosis , Nasal Obstruction/genetics
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