Novel psychoactive substance and other drug use by young adults in Western australia.

There is a lack of information regarding the use of novel psychoactive substances (NPS) in Western Australia. The aim of this study was to pilot-test an online survey to obtain data on the prevalence of NPS and other drug use by young Western Australians aged between 18 and 35 years. The Young Adult Drug and Alcohol Survey (YADAS) was a questionnaire deployed online for a period of six months. Participants were recruited via a combined targeted sampling and snowball methodology. There were 472 valid responses. Overall lifetime use of NPS was relatively high (17.6%), while use in the last year was lower (6.6%). These proportions were comparable to that of cocaine use. The most popular NPS were the synthetic cannabinoids. The proportions of respondents drinking alcohol at risky levels, mixing alcohol with energy drinks, and using pharmaceuticals such as ADHD medications for non-medical reasons were high. The YADAS is the first survey to ascertain the prevalence of use of numerous types of NPS in a large sample of young Western Australian adults. The utilization of an online survey methodology yielded valid results as compared to more intensive surveys, and enables researchers greater flexibility in being able to capture current trends.

Chronic disease and hospitalisation for pandemic (H1N1) 2009 influenza in Indigenous and non-Indigenous Western Australians.

Indigenous and non-indigenous Western Australians with pandemic (H1N1) 2009 influenza (pH1N1) infection were compared for risk factors, influenza vaccination history, symptoms, use of antiviral medications, and hospitalisation. Data were collected systematically on 856 notified cases with laboratory confirmed pH1N1 infection during the first 10 weeks of pH1N1 virus transmission in Western Australia in 2009. Indigenous people with pH1N1 were approximately 3 times more likely to be hospitalised and were more likely to have a range of underlying medical conditions and be smokers, compared with non-Indigenous cases. Age (P < 0.001) and the presence of two or more co-morbidities (P < 0.001) were independent predictors of hospitalisation, while Indigenous status was not, indicating that higher pH1N1 hospitalisation rates in Indigenous Australians during the 2009 winter season were attributable to the higher prevalence of underlying chronic disease. These results underscore the need to ensure that influenza vaccination is delivered as widely as possible among those with chronic health conditions.

Comparison of pandemic (H1N1) 2009 and seasonal influenza, Western Australia, 2009.

We compared confirmed pandemic (H1N1) 2009 influenza and seasonal influenza diagnosed in Western Australia during the 2009 influenza season. From 3,178 eligible reports, 984 pandemic and 356 seasonal influenza patients were selected; 871 (88.5%) and 288 (80.9%) were interviewed, respectively. Patients in both groups reported a median of 6 of 11 symptoms; the difference between groups in the proportion reporting any given symptom was < or =10%. Fewer than half the patients in both groups had > or =1 underlying condition, and only diabetes was associated with pandemic (H1N1) 2009 influenza (odds ratio [OR] 1.9, 95% confidence interval [CI] 1.1-3.5). A total of 129 (14.8%) persons with pandemic (H1N1) 2009 and 36 (12.5%) persons with seasonal influenza were hospitalized (p = 0.22). After controlling for age, we found that patient hospitalization was associated with pandemic (H1N1) 2009 influenza (OR 1.5; 95% CI 1.1-2.1). Contemporaneous pandemic and seasonal influenza infections were substantially similar in terms of patients' symptoms, risk factors, and proportion hospitalized.

Household responses to pandemic (H1N1) 2009-related school closures, Perth, Western Australia.

School closure is often purported to reduce influenza transmission, but little is known about its effect on families. We surveyed families affected by pandemic (H1N1) 2009-related school closures in Perth, Western Australia, Australia. Surveys were returned for 233 (58%) of 402 students. School closure was deemed appropriate by 110 parents (47%); however, 91 (45%) parents of 202 asymptomatic students reported taking >or=1 day off work to care for their child, and 71 (35%) had to make childcare arrangements because of the class closures. During the week, 172 (74%) students participated in activities outside the home on >or=1 occasion, resulting in an average of 3.7 out-of-home activities for each student. In our survey, activities outside the home were commonly reported by students affected by school closure, the effect on families was substantial, and parental opinion regarding school closures as a means to mitigate the outbreak of pandemic (H1N1) 2009 was divided.

The effects of superior semicircular canal dehiscence on the labyrinth: does size matter?

BACKGROUND: Superior semicircular canal dehiscence (SSCD) is characterized by lack of bony covering of the superior semicircular canal in the inner ear, resulting in a third mobile window with altered functioning of the superior semicircular canal. Vertigo in association with sound and pressure changes often occurs. This study examines the relationship between dehiscence size and frequency of sound-induced vertigo. METHOD: Retrospective review of 22 patients with SSCD, noting the auditory frequency producing the maximal electronystagmographic response. RESULTS: The study found a correlation between dehiscence size and stimulator frequency of r = 0.856, p < 0.001. The larger the dehiscence, the lower the frequency of stimuli required to provoke a vestibular response. CONCLUSION: The relationship found between the superior canal dehiscence size and the stimulator frequency has clinical implications in the diagnosis and management of patients with SSCD.

Clinical decision support systems and computer-aided diagnosis in otology.

OBJECTIVES: We reviewed the progress of the implementation of expert diagnostic systems in the field of otology. STUDY DESIGN AND SETTING: We conducted a review of the literature at a research institute. RESULTS: The utilization of expert diagnostic systems in otology is very limited. Previous applications focused primarily upon the diagnosis of vertiginous disorders with the use of deterministic algorithms and, more recently, with adaptive algorithms such as neural networks. CONCLUSION: Expert systems provide greater diagnostic accuracy to physicians across a wide range of medical specialties. The success of such a system depends upon the strength of its reasoning algorithm, the validity of its knowledge base, and its ease of use. SIGNIFICANCE: There have been no attempts to develop an adaptive expert system for the full range of otological conditions. Such a tool may be of great use to physicians as a diagnostic aid and educational resource, particularly for those located in isolated sites.