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1.
Singapore Med J ; 63(1): 47-50, 2022 01.
Article in English | MEDLINE | ID: mdl-35466387

ABSTRACT

The use of implantable cardioverter defibrillators (ICDs) in young women has been increasing in recent years owing to greater awareness about inherited cardiac conditions that increase the risk of sudden death. Traditional placement of ICDs in the infraclavicular region among young women often leads to visible scars, a constant prominence that causes irritation from purse or bra straps and can result in body image concerns and device-related emotional distress. In this case series, two women with long QT syndrome required placement of ICDs for prevention of sudden cardiac death. Submammary placement of ICDs was performed in collaboration with electrophysiologists. We describe our local experience and technique in submammary placement of ICDs as well as the challenges faced.


Subject(s)
Defibrillators, Implantable , Heart Diseases , Death, Sudden, Cardiac/prevention & control , Female , Humans , Prosthesis Implantation/methods , Singapore
2.
J Wound Care ; 30(2): 96-104, 2021 Feb 02.
Article in English | MEDLINE | ID: mdl-33573483

ABSTRACT

OBJECTIVE: To demonstrate the efficacy of the SafeZone UVC (Ushio Inc., Japan) 222 nm ultraviolet C (UVC) light to reduce bacterial burden in pressure ulcers (PUs) in human patients. This research is the first human clinical trial using 222 nm UVC in eradicating bacteria in human wounds. METHOD: Patients with Stage 2 or 3 (as defined by the revised National Pressure Ulcer Advisory Panel Pressure Injury Staging System) sacral or gluteal pressure ulcers (PUs) were subjected to four sessions of 222 nm UVC light therapy over two weeks. Pre- and post-UVC therapy, wound cultures were taken and quantitative analysis of bacterial colony forming units (CFU) were performed. RESULTS: A total of 68 UV light sessions across 16 different patients were conducted. Of these sessions, 59 (87.0%) sessions showed a reduction in CFU counts, with 20 (29.4%) showing complete eradication of bacteria. Bacteria identified included meticillin-resistant Staphylococcus aureus, Pseudomonas aeruginosa and Klebsiella Pneumoniae. The overall median reduction in CFU of the 68 sessions was 78.9%. No adverse events were reported in any of the UV sessions. CONCLUSION: In this study, 222 nm UVC light was safe and effective in reducing bacterial CFU counts in sacral and gluteal PUs across numerous different species of bacteria.


Subject(s)
Disinfection/methods , Ultraviolet Therapy , Wound Healing/physiology , Wound Infection/microbiology , Wound Infection/therapy , Disinfection/instrumentation , Humans , Japan , Lighting , Methicillin-Resistant Staphylococcus aureus , Pilot Projects , Pressure Ulcer/microbiology , Pressure Ulcer/therapy , Staphylococcal Infections/therapy
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