[The development and functioning of embryonic pancreatic islet cells in the anterior chamber of rats]. / Razvitie i funktsionirovanie émbrional'nykh kletok pankreaticheskikh ostrovkov v perednei kamere glaza krys.

In the present study the morphogenesis and differentiation processes in embryonic pancreatic gland implants into Wistar line rat anterior eye chamber have been investigated. The conditions therein were found to be favourable for the endocrine tissue functioning; a number of morphogenetic changes resulting in the formation of islet structure acting as a morphophysiological unit were noted as well. Endocrine cells possess some selective properties as compared to the exocrine tissue. Alloxan diabetic animals demonstrated the most optimum conditions for the endocrine cells development and functioning.

[Implantation of embryonic pancreas into the anterior chamber of healthy and diabetic rats]. / Implantatsiia émbrional'noi podzheludochnoi zhelezy v peredniuiu kameru glaza zdorovym i diabeticheskim krysam.

The possibility of pancreatic-islet embryonic implantation into the frontal chamber of the eye in Wistar rats has been demonstrated. The implantation was followed by the induction of alloxan diabetes. Clinical diabetic compensation has been shown in a number of experimental animals (maximum time of experiments--45 days). The formation of islet-like structures in the frontal chamber of the eye was confirmed microscopically. The structures contained B cells in their cytoplasm. Cellular differentiation leading to the appearance of functionally active endocrine cells has been noted in the implants.