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1.
Microsurgery ; 13(6): 304-12, 1992.
Article in English | MEDLINE | ID: mdl-1453931

ABSTRACT

Reported patency rates after standard end-to-end anastomoses for microvascular prosthetic grafts have been inconsistent and usually disappointing. A modified anastomotic technique is described in which the prosthetic graft is invaginated inside the arterial lumen. In this study of 6 cm lengths of 1 mm internal diameter polytetrafluoroethylene femoro-femoral bypass grafts in the rat, 6 (40%) of 15 grafts with standard anastomoses were patent at 6 months compared to 28 (90%) of 31 grafts using the modified anastomotic technique (P < 0.001). With invagination of the prosthetic graft inside the arterial lumen, reliable high patency rates can be achieved with microvascular prostheses long enough for potential clinical applications.


Subject(s)
Anastomosis, Surgical/methods , Blood Vessel Prosthesis , Femoral Artery/surgery , Polytetrafluoroethylene , Animals , Elastic Tissue/pathology , Endothelium, Vascular/pathology , Femoral Artery/pathology , Graft Occlusion, Vascular/pathology , Male , Microsurgery , Polytetrafluoroethylene/chemistry , Prosthesis Design , Rats , Rats, Wistar , Surface Properties , Suture Techniques , Thrombosis/pathology , Vascular Patency
2.
Early Hum Dev ; 19(2): 147-52, 1989 May.
Article in English | MEDLINE | ID: mdl-2737105

ABSTRACT

An investigation to determine whether there is any relationship between extremes of fetal heart rate during labour and subsequent heart rate at the age of 10 was carried out using data from the 1970 cohort of British Births. In 11,000 nationally representative children it was found that low fetal heart rate (below 120 beats/min) was associated with a heart rate at age 10 which was significantly lower than in those children whose fetal heart rate had remained between 120 and 160 beats/min (P less than 0.01). This relationship could not be explained by fetal asphyxiation, maternal antenatal hypotension or the method of pain relief during labour. There was no equivalent relationship with high fetal heart rate during labour. This could imply that some fetuses with low heart rates are not exhibiting fetal distress but have an inherent tendency to relatively slow heart rates.


Subject(s)
Child , Fetal Heart/physiology , Heart Rate , Pulse , Follow-Up Studies , Humans , Predictive Value of Tests
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