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Nat Prod Res ; 31(23): 2801-2805, 2017 Dec.
Article in English | MEDLINE | ID: mdl-28278644

ABSTRACT

In this study, six known compounds 1-6 were isolated from the aerial parts of Silene arenarioides Desf. using different chromatographic methods. The structures of these compounds were identified as maltol glycoside (1), soyacerebroside I (2), chrysin (3), apigenin (4), quercetin (5) and stigmasterol glucoside (6). The compounds (1) and (2) are reported for the first time from this genus. The isolated compounds were determined using NMR techniques (1H NMR, 13C NMR, COSY, HSQC and HMBC) and mass spectroscopy (ESI-MS). The antibacterial and antioxidant activities of extracts and of compound (1) have been evaluated. The antioxidant activity was performed by DPPH radical scavenging method, which showed that methanol extract possesses a good antioxidant activity with value of IC50 = 8.064 ± 0.005 µg/mL.


Subject(s)
Anti-Bacterial Agents/chemistry , Anti-Bacterial Agents/pharmacology , Antioxidants/chemistry , Antioxidants/pharmacology , Glycosides/chemistry , Glycosides/pharmacology , Silene/chemistry , Apigenin/analysis , Apigenin/pharmacology , Drug Evaluation, Preclinical/methods , Flavonoids/analysis , Flavonoids/chemistry , Glucosides/analysis , Glucosides/pharmacology , Magnetic Resonance Spectroscopy , Molecular Structure , Plant Extracts/chemistry , Plant Extracts/pharmacology , Quercetin/analysis , Quercetin/pharmacology , Spectrometry, Mass, Electrospray Ionization , Stigmasterol/analogs & derivatives , Stigmasterol/analysis , Stigmasterol/pharmacology
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