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1.
Kardiologiia ; 52(11): 92-6, 2012.
Article in Russian | MEDLINE | ID: mdl-23237402

ABSTRACT

According to some data up to 20% of patients with thyrotoxicosis suffer from vasospastic angina. But presence of coronary artery spasm can be rarely confirmed. We describe a case of development of spasm of coronary arteries in a patients with severe thyrotoxicosis. Despite active treatment of thyrotoxicosis and use of drugs aimed at prevention of coronary spasm this patient with minor changes in coronary arteries (according to autopsy data) developed episode of acute myocardial ischemia leading to lethal outcome. This clinical case shows that patients with thyrotoxicosis and documented transitory myocardial ischemia should receive therapy with thyrostatics and drugs preventing coronary spasm in maximal doses until stable normalization of levels of thyroid hormones.


Subject(s)
Antithyroid Agents/administration & dosage , Atrial Fibrillation , Cardiovascular Agents/administration & dosage , Heart Failure , Myocardial Ischemia , Myocardium/pathology , Thyrotoxicosis , Atrial Fibrillation/drug therapy , Atrial Fibrillation/etiology , Atrial Fibrillation/physiopathology , Coronary Angiography , Electrocardiography , Fatal Outcome , Heart Failure/drug therapy , Heart Failure/etiology , Heart Failure/pathology , Heart Failure/physiopathology , Humans , Male , Middle Aged , Myocardial Ischemia/drug therapy , Myocardial Ischemia/etiology , Myocardial Ischemia/pathology , Myocardial Ischemia/physiopathology , Thyrotoxicosis/complications , Thyrotoxicosis/drug therapy , Thyrotoxicosis/physiopathology
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