ABSTRACT
BACKGROUND: New iterative algorithms for scatter compensation (SC), noise suppression, and depth-dependent collimator resolution (RR) can shorten rest and stress SPECT acquisitions by 50% while maintaining quality and accuracy equivalent to conventional scans. Full-time stress-only myocardial perfusion SPECT is accurate and efficient when combined with line-source attenuation correction (LSAC). We investigated the potential for half-time stress-only LSAC-SPECT by comparing this to conventional rest/stress SPECT in patients imaged for suspected CAD at three different centers. METHODS: One hundred and ten patients (58% men, 53% exercise) had 64 projection rest/stress Tc-99m ECG-gated SPECT with simultaneous Gd-153 LSAC: 18 had Subject(s)
Coronary Artery Disease/diagnostic imaging
, Image Enhancement/methods
, Myocardial Perfusion Imaging/statistics & numerical data
, Technetium Tc 99m Sestamibi
, Tomography, Emission-Computed, Single-Photon/statistics & numerical data
, Adult
, Exercise Test/statistics & numerical data
, Humans
, Middle Aged
, Radiopharmaceuticals
, Reproducibility of Results
, Sensitivity and Specificity
, United States/epidemiology
, Young Adult