ABSTRACT
There is evidence for the necessity of reorganizing the indications and volumes of antituberculosis care in the tuberculosis hospitals, as shown by the example of one of the subjects of the Russian Federation. The optimum variant of this reorganization lies in the formula of reduction-consolidation-profiling-efficiency by the quality criteria and, when the regional features are kept in mind, is attainable and its alternative is currently absent.
Subject(s)
Hospitals, Public , Hospitals, Special/methods , Outcome Assessment, Health Care , Tuberculosis/therapy , Humans , RussiaABSTRACT
After prosthetics of the aortal valve 30 patients underwent bicycle ergometry training at the sanatorial stage of rehabilitation. 10 patients who did not undergo bicycle ergometry training made up the control group. The efficacy of bicycle ergometry training was assessed according to the time-course of changes in pump and contractile functions of the heart and oxygen consumption at rest and during bicycle ergometry. Transfer of the patients to a higher functional class, a decrease in the number of threshold reactions, attainment of a higher heart rate and a higher oxygen consumption, capacity for an increase of the stroke index up to the load of 1.0 W/kg and of the level of the myocardial reserve up to 1.5-2.0 W/kg were used as criteria for the effectiveness of bicycle ergometry training. The effectiveness of bicycle ergometry training is also supported by the data obtained on comparison of the findings in the main and control groups.
Subject(s)
Asthma/epidemiology , Environmental Exposure , Asthma/diagnosis , Asthma/etiology , Candida/isolation & purification , Humans , Immunoglobulin E/analysisABSTRACT
27 patients with chronic candidiasis of the skin and mucous membranes have been examined with a view to study the expression of E-receptors and its changes after the incubation of T-lymphocytes with theophylline, levamisole, thymaline and Candida albicans antigen. This study has revealed that, in comparison with healthy persons, most patients show decreased expression of E-receptors, and the character of their changes after incubation with the above-mentioned preparations is essentially different. The deviations revealed in this study have been regarded as the modification of T-cell membranes, which is seemingly one of the reasons of the weak competence of T-cells. In its turn, the expression of E-receptors may be considered as an indicator of the influence of different factors on T-lymphocytes. Substances altering the level of cyclic nucleotides in the cell, the antigenic fractions of the fungal causative agent, the suppression or blocking the action of thymic hormone-like substances may serve as such factors.
Subject(s)
Candidiasis, Chronic Mucocutaneous/immunology , Candidiasis/immunology , Receptors, Immunologic/immunology , T-Lymphocytes/immunology , Adjuvants, Immunologic/pharmacology , Adolescent , Adult , Antigens, Fungal/immunology , Candida albicans/immunology , Child , Child, Preschool , Humans , Leukocyte Count/drug effects , Levamisole/pharmacology , Receptors, Immunologic/drug effects , Rosette Formation , Surface Properties , T-Lymphocytes/drug effects , Theophylline/pharmacology , Thymus Hormones/pharmacologyABSTRACT
Five patients (4 men and 1 woman) afflicted with bronchopulmonary aspergillosis (ABPA) were examined. The main criteria for the diagnosis were a high level of the total IgE, demonstration of specific IgE to Aspergillus fumigatus, positive skin tests with antigens of moldy fungi. All the 4 patients with active process, not given corticosteroids, manifested eosinophilia of the sputum and peripheral blood. The clinical picture of bronchial asthma was recorded in 2 patients. It is desirable that all the patients with protracted and relapsing infiltrative processes in the lungs running with sputum and blood eosinophilia undergo examinations for the presence of ABPA.
