ABSTRACT
Cellulosimicrobium cellulans represents a rare human pathogen. Infections have been reported in immunocompromised hosts or in patients with an underlying disease. The authors describe a rare case of early-onset neonatal sepsis due to Cellulosimicrobium cellulans in an infant without any underlying disease. The infant was successfully treated with vancomycin.
Subject(s)
Actinomycetales Infections/microbiology , Actinomycetales/isolation & purification , Bacteremia/microbiology , Actinomycetales/drug effects , Actinomycetales Infections/drug therapy , Anti-Bacterial Agents/pharmacology , Anti-Bacterial Agents/therapeutic use , Bacteremia/drug therapy , Humans , Infant, Newborn , Male , Vancomycin/pharmacology , Vancomycin/therapeutic useABSTRACT
Infections by Leuconostoc species bacteria are uncommon, and usually affect patients with an underlying disease, or those fitted with a venous catheter or subjects previously treated with vancomycin. The most common clinical presentation is fever secondary to a central venous line infection. We report a case of Leuconostoc sp. bacteremia in an otherwise apparently healthy 2.5 month-old infant. The patient was successfully treated with cefotaxime. Leuconostoc sp. is an emerging pathogen that should be considered in the differential diagnosis of vancomycin-resistant Gram-positive bacteremia.
Subject(s)
Bacteremia/microbiology , Gram-Positive Bacterial Infections/microbiology , Leuconostoc/isolation & purification , Anti-Bacterial Agents/therapeutic use , Bacteremia/drug therapy , Cefotaxime/therapeutic use , Female , Gram-Positive Bacterial Infections/drug therapy , Humans , InfantABSTRACT
We describe a child with manifestations of the oculo(facio)-auriculo-vertebral spectrum and caudal dysgenesis. This is the sixth axial mesodermal dysplasia sequence case to be reported. The infant was ascertained through the Spanish Collaborative Study of Congenital Malformations (ECEMC). It was possible to calculate the prevalence figure for the association of both conditions in the same child, as well as its expected chance frequency. Comparison of the expected with the observed frequency supports the suggestion that the concurrence of oculo(facio)-auriculo-vertebral sequence and caudal dysgenesis could well constitute a single entity.
Subject(s)
Abnormalities, Multiple/classification , Goldenhar Syndrome/classification , Mesoderm , Sacrum/abnormalities , Abnormalities, Multiple/epidemiology , Fatal Outcome , Goldenhar Syndrome/epidemiology , Humans , Infant, Newborn , Male , Prevalence , Urinary Tract/abnormalitiesABSTRACT
We report a case of a stillborn infant that presented multiple birth defects and a diploid/tetraploid mosaicism in skin fibroblasts. Clinical and cytogenetical findings are discussed and compared with those presented in previously reported cases.
Subject(s)
Abnormalities, Multiple/genetics , Chromosome Aberrations/genetics , Fetal Death/genetics , Mosaicism , Polyploidy , Prune Belly Syndrome/genetics , Chromosome Disorders , Humans , Infant, Newborn , Lung/abnormalities , Male , Urogenital AbnormalitiesABSTRACT
We report on a male infant with a duplication 9p (pter----q13) and duplication 16p (p13----pter) resulting from a 3:1 meiotic disjunction of a maternal reciprocal translocation. In this case, the mode of segregation fits to the Pachytene-Diagram Model of Jalbert et al [1980]. The infant showed clinical features that have been described both in dup(16p) and in dup(9p). To our knowledge, this is the first time that this unbalanced karyotype has been reported.
